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Intermolecular Multiple Quantum Coherence (iMQC)
phenomenon is a new contrast mechanism for the high
resolution NMR/MRI. iMQC signal directly correlates
with the degree 3D magnetization profile created by
the CRAZED pulse sequence is spatially averaged over
the targeted distance scale. In this book, after the
short introduction, numerical simulation of the iMQC
experiment is given. That includes relaxation
processes, instantaneous radio frequency pulses and
gradients as well as original phase cycling, phantom
positioning and rotation techniques. For the rat
sciatic nerve iMQC signal is studied as a function of
sample orientation as well as correlation gradients
direction and strength and later compared
to the data from uniform water sample. The fixed
mouse fibrotic liver samples are then studied under
different orientations of the CRAZED gradients. All
results are verified by numerical simulations.The new
experimental data and its analysis may be of
interest for students and professional scientists
working in MRI and MR spectroscopy of biological samples.
phenomenon is a new contrast mechanism for the high
resolution NMR/MRI. iMQC signal directly correlates
with the degree 3D magnetization profile created by
the CRAZED pulse sequence is spatially averaged over
the targeted distance scale. In this book, after the
short introduction, numerical simulation of the iMQC
experiment is given. That includes relaxation
processes, instantaneous radio frequency pulses and
gradients as well as original phase cycling, phantom
positioning and rotation techniques. For the rat
sciatic nerve iMQC signal is studied as a function of
sample orientation as well as correlation gradients
direction and strength and later compared
to the data from uniform water sample. The fixed
mouse fibrotic liver samples are then studied under
different orientations of the CRAZED gradients. All
results are verified by numerical simulations.The new
experimental data and its analysis may be of
interest for students and professional scientists
working in MRI and MR spectroscopy of biological samples.