Insulin-like Growth Factors and Cancer

From Basic Biology to Therapeutics
Herausgegeben:Leroith, Derek

• Broschiertes Buch

Produktbeschreibung

The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.

Produktdetails

• Cancer Drug Discovery and Development
• Verlag: Humana / Springer US / Springer, Berlin
• Artikelnr. des Verlages: 978-1-4614-2962-3
• 2012
• Seitenzahl: 296
• Erscheinungstermin: 24. Oktober 2013
• Englisch
• Abmessung: 235mm x 155mm x 17mm
• Gewicht: 456g
• ISBN-13: 9781461429623
• ISBN-10: 1461429625
• Artikelnr.: 40560562

Inhaltsangabe

Preface.- Epidemiology of IGF-1 and Cancer.- Aging and Cancer: The IGF-I Connection.- Obesity, Type 2 Diabetes and Cancer.- IGF System and Breast Cancer.- The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression.- Mouse Models of IGF-1 Deficiency.- Insulin-like Growth Factor Signaling in Pediatric Sarcomas.- Cancer Genes, Tumor Suppressors, and Regulation of IGF-1R Expression in Cancer.- Mouse Models of IGF-1R and Cancer.- Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy.- Targeting Insulin-like Growth Factor (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer.- Calories and Cancer: The Role of Insulin-like Growth Factor.- Cancer Cell Metabolism.- Overlaps between the Insulin and IGF-1R and Cancer.- Index