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Related some last reference (1) it is showed the IN VITRO profile of action of some m-Rna covid vaccine not only to Produce translate for the production of the Spike protein but also the INTRACELLULAR reverse trascription in some human cells.In this study it was verified effect on different times: at 6- 24- 48 hours and the results are clear.Related this aspects it is needed to be verified during the time 3-6- 12 -24 and more time month what happen.This can be useful to complete the profile of security for spike protein molecules production inducers related also this aspect.