Iron-Containing Enzymes

Versatile Catalysts of Hydroxylation Reactions in Nature
Herausgeber: de Visser, Samuel P; Kumar, Devesh

• Gebundenes Buch

Produktbeschreibung

This book explains the mechanism and function of mononuclear iron containing enzymes. These important bioprocess intermediates have great industrial potential.

Produktdetails

• Verlag: Royal Society of Chemistry
• Seitenzahl: 462
• Erscheinungstermin: 1. September 2011
• Englisch
• Abmessung: 245mm x 164mm x 32mm
• Gewicht: 846g
• ISBN-13: 9781849731812
• ISBN-10: 1849731810
• Artikelnr.: 33321751

Autorenporträt

Dr. Sam P. de Visser is based at the Manchester Interdisciplinary Biocenter and School of Chemical Engineering and Analytical Science in Manchester, UK. His research interests include the study of enzyme function and mechanism using theoretical chemistry techniques and the investigation of mononuclear and binuclear dimetal oxidants of substrate monoxygenation, dioxygenation and dehydrogenation. Dr Visser gained his M.Sc. and Ph.D from the University of Amsterdam in The Netherlands. His postdoctoral research was at King's College London and then the Hebrew University of Jerusalem. He has written several review articles and numerous research papers and has acted as a regular reviewer for numerous research journals. He also Guest Edited a special issue of the Journal of Physical Chemistry - A on "Sason Shaik Festschrift". He is a member of a number of scholarly societies and the winner of the Ramsay Memorial Fellowship of the Royal Netherlands Academy of Arts and Sciences (1997) and the Lise Meitner Minerva Junior Award from the Israel Chemical Society (2003). Dr. Devesh Kumar his based at the Max-Planck-Institut f³r Kohlenforschung, Germany. His research interests include studies of the reactivity of organic substrates with metalloenzymes or biomimetic catalysts and Simulations of intermolecular interactions in mesogens and biological molecules. Dr Kumar obtained is M.Sc. and Ph.D from Gorakhpur University in India. His postdoctoral research, before joining the The Max-Planck-Institut f³r Kohlenforschung, was at Nagarjuna University in India and The Hebrew University of Jerusalem. He has written several review articles and numerous research papers and has acted as a regular reviewer for numerous research journals. He has also delivered several important lectures and is a member of the Indian Biophysics Society. Devesh Kumar is Assistant Editor of Nanoscale Research Letters and has Guest Edited two special issues of the Journal of Physical Chemistry - A.

Inhaltsangabe

Nonheme iron(IV)-oxo oxidants in enzymes: Spectroscopic properties and
reactivity patterns; Heme iron(IV)-oxo oxidants in enzymes: Spectroscopic
properties and reactivity patterns; Mechanism and function of taurine/
-ketoglutarate dioxygenase enzymes, an update; Mechanism and function of
cysteine dioxygenase enzymes; Mechanism and function of heme peroxidase
enzymes; Mechanism and function of cytochrome P450 enzymes Biomimetic
studies of mononuclear nonheme iron containing oxidants; Biomimetic studies
of mononuclear porphyrin containing oxidants; Density functional
calibration studies on iron-containing systems; Density functional theory
studies on isomerisation reactions catalyzed by cytochrome P450 enzymes
Quantum mechanics/molecular mechanics studies of peroxidase enzymes;
Theoretical modelling of nonheme iron containing oxidants