The aim of the book is to introduce the reader to the kinetic analysis of a wide range of biological processes at the molecular level. It is intended to show that the same approach can be used to resolve the number of steps in enzyme reactions, muscle contraction, visual perception and ligand binding receptors that trigger other physiological processes. Attention is also given to methods for characterizing these steps in chemical terms. Although the treatment is mainly theoretical, a wide range of examples and experimental techniques are also introduced and an historical approach is used to…mehr
The aim of the book is to introduce the reader to the kinetic analysis of a wide range of biological processes at the molecular level. It is intended to show that the same approach can be used to resolve the number of steps in enzyme reactions, muscle contraction, visual perception and ligand binding receptors that trigger other physiological processes. Attention is also given to methods for characterizing these steps in chemical terms. Although the treatment is mainly theoretical, a wide range of examples and experimental techniques are also introduced and an historical approach is used to demonstrate the development of the theory and experimental techniques of kinetic analysis in biology.
Part I. The Time Scales of Nature: a Historical Survey: 1. The history of the application of physical principles 2 Kinetics and biological problems 3 Time scales of nature and of measurement Part II. Some Mathematical Introductions: 4. The origins of exponential behaviour 5. Modelling of kinetic systems 6. Data collection, reduction and analysis 7. Guidelines for the derivation of equations used in the text Part III. Elementary Kinetic Equations: Ground Rules: 8. The law of mass action, rates and equilibria 9. The evaluation of first and second order rate constants 10. An introduction to practical steady state kinetics 11. Steady state kinetics of reversible effectors and ionic equilibria Part IV. Kinetic Analysis of Complex Reactions: 12. Introduction to the study of transients and reaction sequences 13. Consecutive reactions and physiological responses Part V. Kinetic Mechanisms of Enzyme Reactions: 14. Transient kinetics and enzyme reactions 15. Sequential enzyme reactions in metabolism and control 16. Kinetics of ligand dissociation and exchange between binding sites Part VI. Chemical Relaxation Phenomena: 17. Applications of relaxation kinetics 18. Basic equations for the analysis of chemical relaxations 19. Chemical relaxation of ligand binding and recognition 20. Relaxations of proton equilibria PartVII. Factors Affecting the Rates of Chemical Reactions 21. Introduction to the history and concepts of chemical dynamics 22. Temperature dependence of reactions and the activation parameters 23. Viscosity and molecular dynamics 24. Diffusion control of reactions 25. Some comments on the use of isotopes in kinetic investigations Part VIII. The Role of Light in Kinetic Investigations 26. Applications of photochemistry 27. Luminescence and other excited states 28. The scope of fluorescence life time studies 29. Photolabile (caged) compounds for the initiation of reactions References Index.
Part I. The Time Scales of Nature: a Historical Survey: 1. The history of the application of physical principles 2 Kinetics and biological problems 3 Time scales of nature and of measurement Part II. Some Mathematical Introductions: 4. The origins of exponential behaviour 5. Modelling of kinetic systems 6. Data collection, reduction and analysis 7. Guidelines for the derivation of equations used in the text Part III. Elementary Kinetic Equations: Ground Rules: 8. The law of mass action, rates and equilibria 9. The evaluation of first and second order rate constants 10. An introduction to practical steady state kinetics 11. Steady state kinetics of reversible effectors and ionic equilibria Part IV. Kinetic Analysis of Complex Reactions: 12. Introduction to the study of transients and reaction sequences 13. Consecutive reactions and physiological responses Part V. Kinetic Mechanisms of Enzyme Reactions: 14. Transient kinetics and enzyme reactions 15. Sequential enzyme reactions in metabolism and control 16. Kinetics of ligand dissociation and exchange between binding sites Part VI. Chemical Relaxation Phenomena: 17. Applications of relaxation kinetics 18. Basic equations for the analysis of chemical relaxations 19. Chemical relaxation of ligand binding and recognition 20. Relaxations of proton equilibria PartVII. Factors Affecting the Rates of Chemical Reactions 21. Introduction to the history and concepts of chemical dynamics 22. Temperature dependence of reactions and the activation parameters 23. Viscosity and molecular dynamics 24. Diffusion control of reactions 25. Some comments on the use of isotopes in kinetic investigations Part VIII. The Role of Light in Kinetic Investigations 26. Applications of photochemistry 27. Luminescence and other excited states 28. The scope of fluorescence life time studies 29. Photolabile (caged) compounds for the initiation of reactions References Index.
Es gelten unsere Allgemeinen Geschäftsbedingungen: www.buecher.de/agb
Impressum
www.buecher.de ist ein Internetauftritt der buecher.de internetstores GmbH
Geschäftsführung: Monica Sawhney | Roland Kölbl | Günter Hilger
Sitz der Gesellschaft: Batheyer Straße 115 - 117, 58099 Hagen
Postanschrift: Bürgermeister-Wegele-Str. 12, 86167 Augsburg
Amtsgericht Hagen HRB 13257
Steuernummer: 321/5800/1497
USt-IdNr: DE450055826
