We characterize eight families of Leucine Rich Repeat (LRR) units in terms of their amino acid sequences and their tertiary structures. Tandem LRRs form helices with a broad range of parameters. These LRR helices have a broad range of functions in eukaryotes, prokaryotes, and viruses. We explore the relationships of these structures to the functions of the LRR proteins and consider their evolution(s).
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