This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine".
This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine".
Preface Preface to the First Edition Acknowledgments Origins of Chapters Introduction SECTION I BROAD CONCEPTS AND ANALYTIC TECHNIQUES Chapter 1 Statistical Concepts Fundamental to Investigations /Lincoln E. Moses Chapter 2 Some Uses of Statistical Thinking /John C. Bailar III Chapter 3 Use of Statistical Analysis in the New England Journal of Medicine /John D. Emerson and Graham A. Colditz SECTION II DESIGN Chapter 4 Designs for Experiments Parallel Comparisons of Treatment /Philip W. Lavoriy Thomas A. Louis, John C. BailarIIIy and Marcia Polansky Chapter 5 Crossover and Self Controlled Designs in Clinical Research /Thomas A. Louis, Philip W. Lavoriy John C. BailarIIIy and Marcia Polansky Chapter 6 Studies without Internal Controls John C. BailarIIIy /Thomas A. Louis, Philip W. Lavoriy and Marcia Polansky Chapter 7 The Series of Consecutive Cases as a Device for Assessing Outcomes of Interventions /Lincoln E. Moses Chapter 8 A Classification for Biomedical Research Reports /John C. Bailar III, Thomas A. Louis, Philip W. Lavori, and Marcia Polansky SECTION III ANALYSIS Chapter 9 Decision Analysis /Stephen G. Pauker and Jerome P. Kassirer Chapter 10 PValues /James H. Ware, Frederick Mosteller, Fernando Delgado, Christl Donnelly, and Joseph A. Ingelfinger Chapter 11 Simple Linear Regression in Medical Research /Katherine Godfrey Chapter 12 Comparing the Means of Several Groups /Katherine Godfrey Chapter 13 Analyzing Data from Ordered Categories /Lincoln E. Moses, John D. Emerson, and Hossein Hosseini Chapter 14 Statistical Analysis of Survival Data /Stephen Lagakos Chapter 15 Contingency Tables in Medical Studies /Daniel Zelterman and Thomas A. Louis SECTION IV COMMUNICATING RESULTS Chapter 16 Guidelines for Statistical Reporting in Articles of Medical Journals /John C. Bailar III and Frederick Mosteller Chapter 17 Reporting on Methods in Clinical Trials /Rebecca DerSimonian, L. Joseph Charettey Bucknam McPeek, and Frederick Mosteller Chapter 18 Statistical Consultation in Clinical Research: A Two Way Street /Lincoln E. Moses and Thomas A. Louis Chapter 19 The Importance of Beta, the Type II Error, and Sample Size in the Design and Interpretation of the Randomized Controlled Trial: Survey of Two Sets of "Negative" Trials /Jennie A. Freiman, Thomas C. Chalmers, Harry Smith, Jr.y and Roy R. Kuebler Chapter 20 Writing about Numbers /Frederick Mosteller SECTION V REVIEWS AND META STUDIES Chapter 21 Medical Technology Assessment /John C. Bailar III and Frederick Mosteller Chapter 22 Combining Results from Independent Investigations: Meta Analysis in Clinical Research /Katherine Taylor Halvorsen, Elisabeth Burdick, Graham A. Colditz, Howard S. Frazier, and Frederick Mosteller Chapter 23 Meta Analyses of Randomized Control Trials: An Update of the Quality and Methodology /Henry S. Sacks, Jayne Berrier, Dinah Reitman, Daniel Pagano, and Thomas C. Chalmers INDEX.
Preface Preface to the First Edition Acknowledgments Origins of Chapters Introduction SECTION I BROAD CONCEPTS AND ANALYTIC TECHNIQUES Chapter 1 Statistical Concepts Fundamental to Investigations /Lincoln E. Moses Chapter 2 Some Uses of Statistical Thinking /John C. Bailar III Chapter 3 Use of Statistical Analysis in the New England Journal of Medicine /John D. Emerson and Graham A. Colditz SECTION II DESIGN Chapter 4 Designs for Experiments Parallel Comparisons of Treatment /Philip W. Lavoriy Thomas A. Louis, John C. BailarIIIy and Marcia Polansky Chapter 5 Crossover and Self Controlled Designs in Clinical Research /Thomas A. Louis, Philip W. Lavoriy John C. BailarIIIy and Marcia Polansky Chapter 6 Studies without Internal Controls John C. BailarIIIy /Thomas A. Louis, Philip W. Lavoriy and Marcia Polansky Chapter 7 The Series of Consecutive Cases as a Device for Assessing Outcomes of Interventions /Lincoln E. Moses Chapter 8 A Classification for Biomedical Research Reports /John C. Bailar III, Thomas A. Louis, Philip W. Lavori, and Marcia Polansky SECTION III ANALYSIS Chapter 9 Decision Analysis /Stephen G. Pauker and Jerome P. Kassirer Chapter 10 PValues /James H. Ware, Frederick Mosteller, Fernando Delgado, Christl Donnelly, and Joseph A. Ingelfinger Chapter 11 Simple Linear Regression in Medical Research /Katherine Godfrey Chapter 12 Comparing the Means of Several Groups /Katherine Godfrey Chapter 13 Analyzing Data from Ordered Categories /Lincoln E. Moses, John D. Emerson, and Hossein Hosseini Chapter 14 Statistical Analysis of Survival Data /Stephen Lagakos Chapter 15 Contingency Tables in Medical Studies /Daniel Zelterman and Thomas A. Louis SECTION IV COMMUNICATING RESULTS Chapter 16 Guidelines for Statistical Reporting in Articles of Medical Journals /John C. Bailar III and Frederick Mosteller Chapter 17 Reporting on Methods in Clinical Trials /Rebecca DerSimonian, L. Joseph Charettey Bucknam McPeek, and Frederick Mosteller Chapter 18 Statistical Consultation in Clinical Research: A Two Way Street /Lincoln E. Moses and Thomas A. Louis Chapter 19 The Importance of Beta, the Type II Error, and Sample Size in the Design and Interpretation of the Randomized Controlled Trial: Survey of Two Sets of "Negative" Trials /Jennie A. Freiman, Thomas C. Chalmers, Harry Smith, Jr.y and Roy R. Kuebler Chapter 20 Writing about Numbers /Frederick Mosteller SECTION V REVIEWS AND META STUDIES Chapter 21 Medical Technology Assessment /John C. Bailar III and Frederick Mosteller Chapter 22 Combining Results from Independent Investigations: Meta Analysis in Clinical Research /Katherine Taylor Halvorsen, Elisabeth Burdick, Graham A. Colditz, Howard S. Frazier, and Frederick Mosteller Chapter 23 Meta Analyses of Randomized Control Trials: An Update of the Quality and Methodology /Henry S. Sacks, Jayne Berrier, Dinah Reitman, Daniel Pagano, and Thomas C. Chalmers INDEX.
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