Main description:
The microvasculature refers to the smallest blood vessels, arterial and venous, that nurture the tissues of each organ. Apart from transport, they also contribute to the systematic regulation of the body. In everyday terminology, the microcirculation is "where the action is." Microcirculation is directly involved in such disease states as Alzheimers, inflammation, tumor growth, diabetic retinopathy, and wound healing- plus cardiovascular fitness is directly related to the formation of new capillaries in large muscles. Microvascular Research is the first book devoted exclusively to this vital systemic component of the cardiovascular system and provides up to date mini-reviews of normal functions and clinical states. The contributing authors are senior scientists with international reputation in their given disciplines.
This two-volume set is a broad, interdisciplinary work that encompasses basic research and clinical applications equally.
- Broad coverage of both basic and clinical aspects of microvasculature research
- Contains 167 chapters from over 300 international authors
- Each chapter includes key figures and annotated references
Review quote:
"Shepro and his coeditors pack an abundance of facts and ideas into this comphrehensive set of minireviews that will propel our understanding of the microcirulation forward and encourage the next round of research and practice in the field. This book is an important contribution worth the attention of anyone who hopes to understand the biologic systems that are fundamental to the practice of medicine."
--Andrew S. Greene, Medical College of Wisconsin, in NEW ENGLAND JOURNAL OF MEDICINE (October 26, 2006)
"...anyone looking to review an area of microvascular disease or study could easily find what he or she needs in this text. Indeed, any student, novice, or experienced professional would value owning this new text as a reference for their work. The two-volume set is well illustrated and the editorial board has done a superb job in coordinating the figures and photographs to lend to a cohesive format. In sum, this is a powerful text that will endure for years...It will serve well anyone beginning or active in a career in microvascular health and disease, vascular biology, or endothelial cell function."
- Marc A. Silver, Director, Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, IL, U.S.A. for CONGESTIVE HEART FAILURE (Aug 2006)
"...I found the nearly 1200 pages a very useful reference. ...Microvascular Research
provides a useful compendium of microvascular models
in a myriad of organ systems that is helpful in generating new hypotheses and approaches in any organ system of interest. Every integrative biology laboratory should own a copy."
- Richard P. Shannon, MD, Allegheny General Hospital
Drexel University College of Medicine, Pittsburgh, Pa, U.S.A. for CIRCULATION, Journal of the American Heart Association (2006)
"...has the potential, especially with the future electronic updates, to become a widely used resource by anyone in the field of microvascular biology."
- Doody's: 3 Stars (April 2006)
Table of contents:
BASIC SCIENCE
Cell Biology
Vascular Development: Vasculogenesis and Angiogenesis
In Vivo Models
Permeability, Tone and Hemodynamics
Transport, Junctions, Adhesion Molecules
ORGAN MICROVASCULAR ADAPTATIONS
Cardiology
Central Nervous System and Eye
Gastrointestinal Tract
Hematopoietic System
Kidney
Liver
Lung
Lymphatics
Pancreas
Skeletal Muscle
Skin
Reproductive Systems
PATHOLOGY
Alzheimer's
Acute Respiratory Distress Syndrome
Arthritis
Blood, Thrombosis and Homeostasis
Coronary Slow Flow
Diabetes
Hemorrhagic Fever Viruses
Hypercholesterolemia
Hypertension
Inflammation
Immunology
Kidney Transplant Rejection
Leak Syndrome
Lung Injury
Organ Transplantation
Periodontal Disease
Pollutants
Pre-eclampsia
Wound Healing
Sclerosis
Skin
Tumors
Vasculitis
THERAPY
Hemorrhagic Shock
Preconditioning
Statins
Therapeutic Angiogenesis
Vascular Endothelium
NEW RESEARCH MODES AND PROCEDURES
DNA Microarray
Engineered Tissue
Endothelial Biomarker
Knockout/transgenic Models
Mathematical Models
Proteomics
Stem Cells
The microvasculature refers to the smallest blood vessels, arterial and venous, that nurture the tissues of each organ. Apart from transport, they also contribute to the systematic regulation of the body. In everyday terminology, the microcirculation is "where the action is." Microcirculation is directly involved in such disease states as Alzheimers, inflammation, tumor growth, diabetic retinopathy, and wound healing- plus cardiovascular fitness is directly related to the formation of new capillaries in large muscles. Microvascular Research is the first book devoted exclusively to this vital systemic component of the cardiovascular system and provides up to date mini-reviews of normal functions and clinical states. The contributing authors are senior scientists with international reputation in their given disciplines.
This two-volume set is a broad, interdisciplinary work that encompasses basic research and clinical applications equally.
- Broad coverage of both basic and clinical aspects of microvasculature research
- Contains 167 chapters from over 300 international authors
- Each chapter includes key figures and annotated references
Review quote:
"Shepro and his coeditors pack an abundance of facts and ideas into this comphrehensive set of minireviews that will propel our understanding of the microcirulation forward and encourage the next round of research and practice in the field. This book is an important contribution worth the attention of anyone who hopes to understand the biologic systems that are fundamental to the practice of medicine."
--Andrew S. Greene, Medical College of Wisconsin, in NEW ENGLAND JOURNAL OF MEDICINE (October 26, 2006)
"...anyone looking to review an area of microvascular disease or study could easily find what he or she needs in this text. Indeed, any student, novice, or experienced professional would value owning this new text as a reference for their work. The two-volume set is well illustrated and the editorial board has done a superb job in coordinating the figures and photographs to lend to a cohesive format. In sum, this is a powerful text that will endure for years...It will serve well anyone beginning or active in a career in microvascular health and disease, vascular biology, or endothelial cell function."
- Marc A. Silver, Director, Heart Failure Institute, Advocate Christ Medical Center, Oak Lawn, IL, U.S.A. for CONGESTIVE HEART FAILURE (Aug 2006)
"...I found the nearly 1200 pages a very useful reference. ...Microvascular Research
provides a useful compendium of microvascular models
in a myriad of organ systems that is helpful in generating new hypotheses and approaches in any organ system of interest. Every integrative biology laboratory should own a copy."
- Richard P. Shannon, MD, Allegheny General Hospital
Drexel University College of Medicine, Pittsburgh, Pa, U.S.A. for CIRCULATION, Journal of the American Heart Association (2006)
"...has the potential, especially with the future electronic updates, to become a widely used resource by anyone in the field of microvascular biology."
- Doody's: 3 Stars (April 2006)
Table of contents:
BASIC SCIENCE
Cell Biology
Vascular Development: Vasculogenesis and Angiogenesis
In Vivo Models
Permeability, Tone and Hemodynamics
Transport, Junctions, Adhesion Molecules
ORGAN MICROVASCULAR ADAPTATIONS
Cardiology
Central Nervous System and Eye
Gastrointestinal Tract
Hematopoietic System
Kidney
Liver
Lung
Lymphatics
Pancreas
Skeletal Muscle
Skin
Reproductive Systems
PATHOLOGY
Alzheimer's
Acute Respiratory Distress Syndrome
Arthritis
Blood, Thrombosis and Homeostasis
Coronary Slow Flow
Diabetes
Hemorrhagic Fever Viruses
Hypercholesterolemia
Hypertension
Inflammation
Immunology
Kidney Transplant Rejection
Leak Syndrome
Lung Injury
Organ Transplantation
Periodontal Disease
Pollutants
Pre-eclampsia
Wound Healing
Sclerosis
Skin
Tumors
Vasculitis
THERAPY
Hemorrhagic Shock
Preconditioning
Statins
Therapeutic Angiogenesis
Vascular Endothelium
NEW RESEARCH MODES AND PROCEDURES
DNA Microarray
Engineered Tissue
Endothelial Biomarker
Knockout/transgenic Models
Mathematical Models
Proteomics
Stem Cells