Lela BuckinghamMolecular Diagnostics
Fundamentals, Methods, and Clinical Applications
College of Health Sciences, Rush University Medical Center, Chicago, IL
Section I Fundamentals of Molecular Biology
Chapter 1: Nucleic Acids
Chapter 2: Genotype to Phenotype
Chapter 3: Gene Expression and Epigenetics
Section II Common Techniques in Molecular Biology
Chapter 4: Collection, Isolation and Quantification of Nucleic Acids
Chapter 5: Resolution and Detection of Nucleic Acids
Chapter 6: Analysis and Characterization of Nucleic Acids and Proteins
Chapter 7: Nucleic Acid Amplification
Chapter 8: Human Chromosomal Structure and Structural Variants
Chapter 9: Targeted Variant Detection
Chapter 10: Molecular Sequencing
Section III Molecular Techniques in the Clinical Laboratory
Chapter 11: Molecular Variants and Human Identification
Chapter 12: Detection and Identification of Microorganisms
Chapter 13: Molecular Detection of Inherited Diseases
Chapter 14: Molecular Oncology
Chapter 15: DNA-Based Tissue Typing
Chapter 16: Quality Assurance and Quality Control in the Molecular
Laboratory
Appendix A: Study Question Answers
Appendix B: Answers to Case Studies
Glossary
Index