This textbook aims to describe in a condensed form the essentials of molecular immunology behind bacterial infections, the microbiome, viral infections (such as influenza and COVID-19), organ transplantations, autoimmunity, allergy and tumor immunology. The book emphasizes the impact of immunology in maintaining our health and preventing disease. Our immune system protects us not only from severe consequences of infectious diseases and getting cancer, but is also able to harm us severely via sepsis, cytokine storms and anaphylactic shocks. Molecular understanding of immunology should allow the…mehr
This textbook aims to describe in a condensed form the essentials of molecular immunology behind bacterial infections, the microbiome, viral infections (such as influenza and COVID-19), organ transplantations, autoimmunity, allergy and tumor immunology. The book emphasizes the impact of immunology in maintaining our health and preventing disease. Our immune system protects us not only from severe consequences of infectious diseases and getting cancer, but is also able to harm us severely via sepsis, cytokine storms and anaphylactic shocks. Molecular understanding of immunology should allow the reader a more rational handling of common diseases, most of which are associated with chronic inflammation.
Carsten Carlberg graduated in 1989 with a Ph.D. in biochemistry at the Free University Berlin (Germany). After positions as Postdoc at Roche (Basel, Switzerland), Group Leader at the University of Geneva (Switzerland) and Docent at the University of Düsseldorf (Germany), he is since 2000 Full Professor of biochemistry at the University of Eastern Finland in Kuopio (Finland). Since 2022, Prof. Carlberg is ERA Chair for nutrigenomics at the Polish Academy of Science. His work focuses on mechanisms of gene regulation by nuclear hormones, in particular on vitamin D. At present, Prof. Carlberg's projects focus on epigenome-wide effects of vitamin D on the human immune system in the context of cancer. Stine Marie Ulven graduated in 2000 with a Ph.D. in nutrition at the University of Oslo (Norway). Since 2015 she is professor at the Department of Nutrition, Institute of Basic Medical Sciences at the University of Oslo (Norway). The main research interests of Prof. Ulven are human dietary intervention studies and diet-gene interactions with particular focus on the role of dietary fat in prevention of chronic diseases. Eunike Velleuer graduated in 2006 as M.D. at the University of Düsseldorf (Germany) and specialized in 2016 in pediatric hemato-oncology. At present, she serves as Senior Physician at the Helios Children's Clinic Krefeld as well as Research Associate at the University of Düsseldorf. Her special clinical focus is the cancer predisposition syndrome Fanconi anemia. Herein, her research interest is early detection and prevention of oral squamous cell carcinoma. Furthermore, Dr. Velleuer is interested in increasing patients' resilience and finding alternative ways for long-lasting empowerment.
Inhaltsangabe
1 Cells and tissues of the immune system.- 2 Innate immunity and inflammation.- 3 Adaptive immunity and antigen receptor diversity.- 4 B cell immunity: BCRs, antibodies and their effector functions.- 5 Antigen-presenting cells and the major histocompatibility complex.- 6 T cell immunity: TCRs and their effector functions.- 7 Immunity to bacterial pathogens and the microbiome.- 8 Immunity to viral pathogens and the virome.- 9 Tolerance and transplantation immunology.- 10 Immunological hypersensitivities: Allergy and autoimmunity.- 11 Cancer immunology.
1 Cells and tissues of the immune system.- 2 Innate immunity and inflammation.- 3 Adaptive immunity and antigen receptor diversity.- 4 B cell immunity: BCRs, antibodies and their effector functions.- 5 Antigen-presenting cells and the major histocompatibility complex.- 6 T cell immunity: TCRs and their effector functions.- 7 Immunity to bacterial pathogens and the microbiome.- 8 Immunity to viral pathogens and the virome.- 9 Tolerance and transplantation immunology.- 10 Immunological hypersensitivities: Allergy and autoimmunity.- 11 Cancer immunology.
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