At the frontier of modern medicine lies a revolution in drug delivery systems that operates at the scale of billionths of a meter. Nanocarriers for Nucleic Acids and Proteins presents a comprehensive exploration of these groundbreaking technologies that are reshaping therapeutic approaches across medical science. From fundamental concepts to cutting-edge applications, this comprehensive volume brings together world-class researchers to provide an in-depth examination of: Design principles and characteristics of various nanocarrier systemsAdvanced delivery mechanisms for nucleic acids and…mehr
At the frontier of modern medicine lies a revolution in drug delivery systems that operates at the scale of billionths of a meter. Nanocarriers for Nucleic Acids and Proteins presents a comprehensive exploration of these groundbreaking technologies that are reshaping therapeutic approaches across medical science.
From fundamental concepts to cutting-edge applications, this comprehensive volume brings together world-class researchers to provide an in-depth examination of: Design principles and characteristics of various nanocarrier systemsAdvanced delivery mechanisms for nucleic acids and proteinsBreakthrough applications in gene therapy and cancer immunotherapyCritical aspects of translating laboratory success to clinical implementation Featuring detailed coverage of lipid-based, polymer-based, inorganic, and bio-inspired nanocarriers, this essential resource bridges the gap between theoretical understanding and practical application. Whether you are developing new therapeutic approaches, optimizing delivery systems, or exploring the frontiers of nanomedicine, this comprehensive guide provides the insights and frameworks needed to advance your work.
Luis H. Reyes, PhD, is an associate professor at Universidad de Los Andes (Bogotá, Colombia), where he leads research at the intersection of biological engineering and therapeutic delivery systems. He holds a BS in Chemical Engineering from Universidad Industrial de Santander (Colombia) and a PhD in Chemical Engineering from Texas A&M University. Juan C. Cruz, PhD, is a distinguished researcher and engineer at the Department of Biomedical Engineering, Universidad de Los Andes (Bogotá, Colombia), where he has been advancing the frontiers of nanobiotechnology since 2016. He holds a BS in Chemical Engineering from the National University of Colombia and earned his PhD in Chemical Engineering from Kansas State University, where his innovative work established a new platform for enzyme immobilization for applicstions in non-aqueous media. Yashwant V. Pathak received his PhD from Nagpur University, India, Executive MBA and Masters in Conflict Management, Sullivan University, Louisville, KY, USA. He has over 45 years' experience in Academia and Industry. Presently, he is Professor and Associate Dean for Faculty Affairs at Taneja College of Pharmacy, University of South Florida, Tampa, FL, USA. Yashwant has published over 400 research papers, reviews and chapters with close to 5000 citations in Google Scholar. He edited over 70 books in nanotechnology, nutraceuticals, drug delivery systems, artificial intelligence, and artificial neural network. He has keen interest in conflict management and edited several books in the areas of organizational conflict management, handbook of organizational conflict management, Eastern and Indigenous perspectives in conflict management, RSS way of resolving conflicts and these two volumes on nonprofit organizations' conflict management.
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Chapter 1: Introduction to Nanocarriers for Nucleic Acids and Proteins. Juan C. Cruz Yashwant V Pathak and Luis H. Reyes Chapter 2: Design Principles of Nanocarriers: Size Shape and Surface Properties Stimuli-Responsive Systems. Juan C. Cruz Luis H. Reyes Chapter 3: Lipid-Based Nano Carriers for Nucleic Acids and Proteins: Liposomes solid lipid nanoparticles nanostructured lipid carriers Biswajit Basu Ayon Dutta Dipanjana Ash Bhupendra Prajapati* Swarupananda Mukherjee Chapter 4: Polymer-based nanocarriers: dendrimers polymeric micelles hydrogels Juan C. Cruz and Luis H. Reyes Chapter 5: Inorganic nano carriers: gold nanoparticles iron nanoparticles silica nanoparticles quantum dots Juan C. Cruz and Luis H. Reyes Chapter 6: Carbon-based nano carriers: Carbon nanotubes graphene oxide fullerenes and Carbon dots Cristian F. Rodríguez Paula Guzmán-Sastoque Coryna Rodriguez-Bazurto Juan C. Rojas-Hernández Luis H. Reyes Juan C. Cruz Chapter 7 : Virus Inspired Nano Carriers Ankita Alice Singh Seema Kohli Chapter 8: Nucleic acid nano carriers DNA nanostructures RNA nanostructures hybrid nucleic acid systems Komal Parmar and Jayvadan Patel Chapter 9 : Protein-based nano carriers: protein cages self-assembling peptides fusion proteins Nishant B. Chopade Prashant K. Deshmukh and Mahesh P. More Chapter 10 : Nanocarrier Functionalization Strategies: Targeting Ligands Imaging Agents stimuli-responsive Elements Sampada Satish Shinde Bhavna Sonule Lalit Kumar Chapter 11: Delivery of nucleic acids using nano carriers: siRNA and miRNA delivery mRNA and DNA delivery CRISPR-Cas systems Paula Guzmán-Sastoque María Camila Monsalve Cristian F. Rodríguez Stiven Castellanos Juan C. Cruz and Luis H. Reyes Chapter 12: Delivery of proteins using nanocarriers: enzymes antibodies and growth factors Jennifer Suurbaar Frederick Sarfo-Antwi Seth Kwabena Amponsah Chapter 13 : Nanocarrier in gene therapy Sinjini Sarkar Swarupananda Mukherjee Shilpa Chatterjee Biswajit Basu Dipanjan Karati Bhupendra Prajapati Chapter 14: Nanocarriers in Cancer Immunotherapy: Personalized Cancer Vaccines Immune Checkpoint Modulation Adoptive T-Cell Therapy Vineet Mahajan and Yashwant Pathak Chapter 15: Future perspectives and challenges: clinical translation and regulatory aspects scale-up and manufacturing ethical considerations Aparoop Das Kalyani Pathak Riya Saikia Manash Pratim Pathak Urvashee Gogoi Dibyajyoti Das Jon Jyoti Sahariah Saptasikha Gogoi and Sukanya Sonowa Chapter 16: Regulatory Toxicology of Biologics: Safeguarding Health in Biotherapeutic Development Satish Rojekar Nishant Talati Shahin Vhora Nidhi Kotadiya Mitul Talala Ruby Chrisitan Vikas Jain Tosha Pandya Disha Suthar and Kinjal Parikh
Chapter 1: Introduction to Nanocarriers for Nucleic Acids and Proteins. Juan C. Cruz Yashwant V Pathak and Luis H. Reyes Chapter 2: Design Principles of Nanocarriers: Size Shape and Surface Properties Stimuli-Responsive Systems. Juan C. Cruz Luis H. Reyes Chapter 3: Lipid-Based Nano Carriers for Nucleic Acids and Proteins: Liposomes solid lipid nanoparticles nanostructured lipid carriers Biswajit Basu Ayon Dutta Dipanjana Ash Bhupendra Prajapati* Swarupananda Mukherjee Chapter 4: Polymer-based nanocarriers: dendrimers polymeric micelles hydrogels Juan C. Cruz and Luis H. Reyes Chapter 5: Inorganic nano carriers: gold nanoparticles iron nanoparticles silica nanoparticles quantum dots Juan C. Cruz and Luis H. Reyes Chapter 6: Carbon-based nano carriers: Carbon nanotubes graphene oxide fullerenes and Carbon dots Cristian F. Rodríguez Paula Guzmán-Sastoque Coryna Rodriguez-Bazurto Juan C. Rojas-Hernández Luis H. Reyes Juan C. Cruz Chapter 7 : Virus Inspired Nano Carriers Ankita Alice Singh Seema Kohli Chapter 8: Nucleic acid nano carriers DNA nanostructures RNA nanostructures hybrid nucleic acid systems Komal Parmar and Jayvadan Patel Chapter 9 : Protein-based nano carriers: protein cages self-assembling peptides fusion proteins Nishant B. Chopade Prashant K. Deshmukh and Mahesh P. More Chapter 10 : Nanocarrier Functionalization Strategies: Targeting Ligands Imaging Agents stimuli-responsive Elements Sampada Satish Shinde Bhavna Sonule Lalit Kumar Chapter 11: Delivery of nucleic acids using nano carriers: siRNA and miRNA delivery mRNA and DNA delivery CRISPR-Cas systems Paula Guzmán-Sastoque María Camila Monsalve Cristian F. Rodríguez Stiven Castellanos Juan C. Cruz and Luis H. Reyes Chapter 12: Delivery of proteins using nanocarriers: enzymes antibodies and growth factors Jennifer Suurbaar Frederick Sarfo-Antwi Seth Kwabena Amponsah Chapter 13 : Nanocarrier in gene therapy Sinjini Sarkar Swarupananda Mukherjee Shilpa Chatterjee Biswajit Basu Dipanjan Karati Bhupendra Prajapati Chapter 14: Nanocarriers in Cancer Immunotherapy: Personalized Cancer Vaccines Immune Checkpoint Modulation Adoptive T-Cell Therapy Vineet Mahajan and Yashwant Pathak Chapter 15: Future perspectives and challenges: clinical translation and regulatory aspects scale-up and manufacturing ethical considerations Aparoop Das Kalyani Pathak Riya Saikia Manash Pratim Pathak Urvashee Gogoi Dibyajyoti Das Jon Jyoti Sahariah Saptasikha Gogoi and Sukanya Sonowa Chapter 16: Regulatory Toxicology of Biologics: Safeguarding Health in Biotherapeutic Development Satish Rojekar Nishant Talati Shahin Vhora Nidhi Kotadiya Mitul Talala Ruby Chrisitan Vikas Jain Tosha Pandya Disha Suthar and Kinjal Parikh
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