Natural products are rich in bioactive compounds which can be explored for drug development. This new volume, Natural Products in Drug Discovery: Benefits, Challenges and Opportunities, combines the potential of traditional medicine with modern techniques for using products derived from natural sources such as plants, microbes, and marine sources as the basis for drug development. This book presents information on the bioactive potential of natural products with properties that are antimicrobial, immunomodulatory, anti-cancerous, anti-inflammatory, hepatoprotective, antiviral, etc. and their…mehr
Natural products are rich in bioactive compounds which can be explored for drug development. This new volume, Natural Products in Drug Discovery: Benefits, Challenges and Opportunities, combines the potential of traditional medicine with modern techniques for using products derived from natural sources such as plants, microbes, and marine sources as the basis for drug development. This book presents information on the bioactive potential of natural products with properties that are antimicrobial, immunomodulatory, anti-cancerous, anti-inflammatory, hepatoprotective, antiviral, etc. and their usage in drug development. Recent techniques used for the isolation and identification of bioactive ingredients from natural sources have also been covered. The book reviews the latest developments in the field of genomics, transcriptomics, proteomics, and metabolomics for harnessing these natural products for commercial applications. The current status of bioprospection and commercialization of natural products-based drugs have also been reviewed. Combining the potential of traditional medicine with modern techniques for the use of natural products for drug development, the book will serve as a useful reference for biochemists, phytochemists, pharmaceutical R&D professionals, students, and researchers working in the field of drug discovery from natural sources.
Meenakshi Thakur, PhD, is currently an Assistant Professor (Biochemistry) at the College of Horticulture and Forestry (Dr. Yashwant Singh Parmar University of Horticulture and Forestry), Neri, Hamirpur, Himachal Pradesh, India. Dr. Thakur research interests and contributions are on biotic and abiotic stress management in plants by employing various strategies such as use of elicitors/plant-based extracts or essential oils. She has published 29 research and review articles and nine book chapters. She was awarded an INSPIRE fellowship from the Department of Science & Technology (India) in 2011 for her doctorate research. She has won prestigious awards from the Association of Indian Universities, New Delhi, India (2013) and Honorable Jury Mention Certificate in Young Scientist Category by EET, CRS, India (2019). She received a travel grant from the Houghton Trust and British Poultry Science for participation at the 20th Congress of the World Veterinary Poultry Association at Edinburgh, Scotland (United Kingdom). She serves as an academic editor for PLOS One and is also a recognized reviewer for several journals.
Inhaltsangabe
Preface 1. Natural Products as Drug Candidates 2. Traditional Knowledge for Drug Discovery 3. Herbal Healing: Plant-Based Natural Products 4. Natural Products with Antimicrobial Properties 5. Natural Products with Immunomodulatory Properties 6. Natural Products with Anticancer Properties 7. Natural Products with Antiviral Properties 8. Approaches to Develop Drugs from Natural Products 9. Strategies for Isolation and Identification of Bioactive Molecules from Natural Sources 10. Role of Omics in Natural Products-Based Drug Discovery 11. Natural Products from Endophytic Microorganisms 12. Natural Products with Antidiabetic Properties 13. Marine-Derived Natural Products with Anticancer Properties 14. Natural Products as Novel Opportunities for Cathepsin Inhibitors 15. Phytoestrogens in Drug Discovery: A Focus on Mechanisms of Action and Safety Assessment 16. Honey Bee Products with Antimicrobial Properties 17. Natural Products for the Prevention of Leaky Gut 18. Role of Natural Products in the Pharmacotherapy of Osteoporosis 19. Gel-Based Natural Therapeutics: Potential Alternatives to Traditional Drug Delivery Systems in Aquaculture 20. The Promising Role of Natural Products as Neuroprotective Agents 21. Natural Products from Microbes 22. Natural Product Databases: Discovering Natures Riches 23. Bioprospecting and Commercialization of Natural Products Index
Preface 1. Natural Products as Drug Candidates 2. Traditional Knowledge for Drug Discovery 3. Herbal Healing: Plant-Based Natural Products 4. Natural Products with Antimicrobial Properties 5. Natural Products with Immunomodulatory Properties 6. Natural Products with Anticancer Properties 7. Natural Products with Antiviral Properties 8. Approaches to Develop Drugs from Natural Products 9. Strategies for Isolation and Identification of Bioactive Molecules from Natural Sources 10. Role of Omics in Natural Products-Based Drug Discovery 11. Natural Products from Endophytic Microorganisms 12. Natural Products with Antidiabetic Properties 13. Marine-Derived Natural Products with Anticancer Properties 14. Natural Products as Novel Opportunities for Cathepsin Inhibitors 15. Phytoestrogens in Drug Discovery: A Focus on Mechanisms of Action and Safety Assessment 16. Honey Bee Products with Antimicrobial Properties 17. Natural Products for the Prevention of Leaky Gut 18. Role of Natural Products in the Pharmacotherapy of Osteoporosis 19. Gel-Based Natural Therapeutics: Potential Alternatives to Traditional Drug Delivery Systems in Aquaculture 20. The Promising Role of Natural Products as Neuroprotective Agents 21. Natural Products from Microbes 22. Natural Product Databases: Discovering Natures Riches 23. Bioprospecting and Commercialization of Natural Products Index
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