Neuroprotection and Regeneration in Stroke - Aghazadeh, Hamed;Mosaddeghi Heris, Reza;Forghani, Nasrin
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This book presents an in-depth exploration of the molecular mechanisms underlying neuronal survival and repair after ischemic brain injury. Focusing on the purinergic P2X4 receptor, the book examines how selective small-molecule modulators can influence neuroinflammation, synaptic plasticity, and vascular remodeling in stroke recovery. It integrates experimental findings, pharmacological strategies, and translational perspectives to bridge basic neuroscience with clinical neurotherapeutics. Readers gain a comprehensive understanding of P2X4-mediated signaling pathways, neuroimmune…mehr

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Produktbeschreibung
This book presents an in-depth exploration of the molecular mechanisms underlying neuronal survival and repair after ischemic brain injury. Focusing on the purinergic P2X4 receptor, the book examines how selective small-molecule modulators can influence neuroinflammation, synaptic plasticity, and vascular remodeling in stroke recovery. It integrates experimental findings, pharmacological strategies, and translational perspectives to bridge basic neuroscience with clinical neurotherapeutics. Readers gain a comprehensive understanding of P2X4-mediated signaling pathways, neuroimmune interactions, and drug development challenges. This volume serves as a valuable reference for neuroscientists, pharmacologists, and clinicians seeking novel therapeutic targets for enhancing neuroprotection and promoting post-stroke regeneration.
Autorenporträt
Dr. Hamed Aghazadeh, Pharm.D., M.Pharm.Eng., MBA (Pharma), B.Sc. (Microbiology).Dr. Reza Mosaddeghi Heris, M.D., Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.Dr. Nasrin Forghani, M.D., Neurologist, Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.