This book is intended for graduate students in statistics, data scientists and statisticians in biomedical sciences and public health. As experts in this area, the authors present extensive materials that are balanced between theoretical and practical topics. The statistical applications in real-life examples lead into meaningful interpretations and inferences.
Features:
Provides an overview of parametric and semiparametric methods
Shows smoothing methods for unstructured nonparametric models
Covers structured nonparametric models with time-varying coefficients
Discusses nonparametric shared-parameter and mixed-effects models
Presents nonparametric models for conditional distributions and functionals
Illustrates implementations using R software packages
Includes datasets and code in the authors' website
Contains asymptotic results and theoretical derivations
Both authors are mathematical statisticians at the National Institutes of Health (NIH) and have published extensively in statistical and biomedical journals. Colin O. Wu earned his Ph.D. in statistics from the University of California, Berkeley (1990), and is also Adjunct Professor at the Georgetown University School of Medicine. He served as Associate Editor for Biometrics and Statistics in Medicine, and reviewer for National Science Foundation, NIH, and the U.S. Department of Veterans Affairs. Xin Tian earned her Ph.D. in statistics from Rutgers, the State University of New Jersey (2003). She has served on various NIH committees and collaborated extensively with clinical researchers.
~Jianhua Huang, Texas A&M University
". . . , this book provides a comprehensive review of the structure of longitudinal data, as well as several applicable nonparametric models. It should prove useful for those working with biomedical data, including real world evidence. The focus is on theorems and proofs; references demonstrate the depth of the research. Real life examples are provided in the form of data descriptions, as well as R code and output. These examples will allow the reader to employ the models and gain expertise in the interpretation of the R output."
~Journal of Biopharmaceutical Statistics, Darcy Hille, Merck Research Laboratories
"The authors are to be commended for such a thorough and well written book, which would certainly be of interest to anyone involved in analysing complex longitudinal data or with an interest in nonparametric approaches."
~David Hughes, ISCB Newsletter
"This book gives a good summary of major advances in unstructured nonparametric models, time-varying models (smoothing models), shared-parameter and mixed-effects models and nonparametric models for distributions. It covers methods, theories and applications, presents R codes for programming which is useful for graduate students in statistics, data scientists and statisticians in biomedical sciences and public health."
~ Rózsa Horváth-Bokor (Budakalász), zbMath