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Nurse burnout is a state of physical, emotional, and mental exhaustion caused by prolonged stress and overwork, commonly seen in high-pressure healthcare environments. It is often characterized by emotional exhaustion, depersonalization (a sense of detachment from patients), and a reduced sense of personal accomplishment. Staffing shortages, long shifts, emotional demands, lack of support, administrative burden, and limited autonomy fuel burnout in nurses. Nurse burnout is not just a workforce issue-it directly impacts patient care and outcomes. Addressing burnout through systemic changes such as better staffing, supportive leadership, mental health resources, and work-life balance is essential to safeguard both healthcare workers and the patients they serve.