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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Optimal matching is a sequence analysis method used in social science, to assess the dissimilarity of ordered arrays of tokens that usually represent a time-ordered sequence of socio-economic states two individuals have experienced. Once such distances have been calculated for a set of observations (e.g. individuals in a cohort) classical tools (such as cluster analysis) can be used. The method was tailored to social sciences from a technique originally introduced to study molecular biology (protein or genetic) sequences (see sequence alignment).