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Orofacial pain remains appealing yet inadequately grasped condition in field of oral medicine. Many evidences and theories are emerging in this respect lately as a result of which treatment modalitiesare also diversifying. As far as diagnosis of orofacial pain is concerned, explanation will be found for patient's complaint of pain. Extensive and reasonably adequate diagnostic investigations must be complied, if they also fail then one should probe for mere unusual conditions, sometimes psychiatric evaluation is also recommended. Based on caring and supportive attitude, a correct patient stratification and disciplinary approach will form beneficial standards for application of currentknowledge in treating orofacial pain disorders. Perhaps the most important instructions forthe clinician to remember when managing pain are: Listen carefully, consider all possibilities, cure if you can and manage if you can not cure, but always console.