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Hozirgi vaqtda xolelitiyoz gepatobiliar tizim kasalliklari tarkibida etakchi o'rinni egallaydi. Bu nafaqat katta tibbiy, balki ijtimoiy ahamiyatga ega, chunki yosh va mehnatga layoqatli bemorlar soni yildan-yilga barqaror oshib bormoqda. So'nggi yillarda butun dunyoda, shu jumladan O'zbekistondada xolelitiyoz bilan kasallanishning ko'payishi tendentsiyasi kuzatilmoqda. Xolelitiyoz bilan kasallanishning ko'payishi bilan bir vaqtda uning murakkab shakllari soni ham ortib bormoqda: xoledoxolitiaz stenozli duodenal papillit (SDP) va obstruktiv sariqlik. Shunday qilib, xolelitiyoz va uning duktal asoratlarini davolash muammosi zamonaviy o't yo'llari jarrohligi uchun eng dolzarb masalalardan biridir. So'nggi paytlarda xoledoxolitiaz va stenozli o'n ikki barmoqli ichak papillitini davolash uchun juda ko'p turli xil usullar paydo bo'ldi. Eng keng tarqalgani laparoskopik xoletsistektomiyadan oldingi endoskopik transpapiller aralashuvlar bo'lib, ular xoledoxolitiaz, stenozli duodenal papillit va ularning kombinatsiyasi bilan asoratlangan xolelitiyozni davolashda hozirda "oltin standart" hisoblanadi.