Oxidative Stress and Diabetic Retinopathy - Youness, Eman Refaat; Abdallah, Hanaa Reyad
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Diabetes mellitus is a metabolic disorder of multifactorial origin, characterized by chronic hyperglycemia and disturbances in the metabolism of carbohydrates, fats, and proteins. Individuals with impaired glucose tolerance exhibit hyperglycemia despite having elevated plasma insulin levels, indicating resistance to insulin action. As impaired glucose tolerance progresses to diabetes mellitus, insulin levels decline, suggesting that patients with non-insulin-dependent diabetes mellitus (NIDDM) experience reduced insulin secretion.Diabetic retinopathy is the most common microvascular…mehr

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Produktbeschreibung
Diabetes mellitus is a metabolic disorder of multifactorial origin, characterized by chronic hyperglycemia and disturbances in the metabolism of carbohydrates, fats, and proteins. Individuals with impaired glucose tolerance exhibit hyperglycemia despite having elevated plasma insulin levels, indicating resistance to insulin action. As impaired glucose tolerance progresses to diabetes mellitus, insulin levels decline, suggesting that patients with non-insulin-dependent diabetes mellitus (NIDDM) experience reduced insulin secretion.Diabetic retinopathy is the most common microvascular complication of diabetes. The role of oxidative stress in diabetic retinopathy (DR) has been demonstrated by significant abnormalities in oxidant-antioxidant mechanisms in individuals with diabetes mellitus (DM).
Autorenporträt
Dr. Eman Refaat Youness, MD in Medical Biochemistry, Faculty of Medicine, Cairo University; Professor at the National Research Centre, Egypt. Experienced in experimental design, clinical research, HPLC, oxidative stress, PCR, DNA, and biochemical analysis. Author of numerous international studies; member of global research bodies.