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This book explores the practice of pediatric palliative care in Yaoundé, Cameroon, highlighting an approach adapted to local realities. It clarifies how this form of care meets the needs of children and their families in the face of serious illness. The book deals with the theoretical aspects of pediatric palliative care, defining fundamental principles and ethical issues, and situates it in the specific socio-economic and cultural context of Yaoundé. The author identifies obstacles such as limited access to resources, cultural perceptions of illness and lack of training in palliative care. The book also presents examples of innovation by healthcare professionals in Yaoundé to improve children's quality of life, by relieving pain, offering psychological support and accompanying families through bereavement. It emphasizes a multidisciplinary approach, involving a variety of players for comprehensive, personalized care. Particular attention is paid to adapting to local realities, to the importance of the child and his or her family, and to developing local expertise.