This new volume of Advances in Pharmacology presents pharmacology of the blood brain barrier, focusing on targeting CNS disorders. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.
This new volume of Advances in Pharmacology presents pharmacology of the blood brain barrier, focusing on targeting CNS disorders. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.
1. ABC Transporter Regulation by Signaling at the Blood-Brain Barrier: Relevance to Pharmacology David S. Miller 2. P-glycoprotein Trafficking as a Therapeutic Target to Optimize CNS Drug Delivery Thomas P. Davis, Lucy Sanchez-Covarubias and Margaret E. Tome 3. Functional Expression of Drug Transporters in Glial Cells: Potential Role on Drug Delivery to the CNS Tamima Ashraf, Amy Kao and Reina Bendayan 4. Blood-Brain Barrier Na Transporters in Ischemic Stroke Martha E. O'Donnell 5. Transcytosis of Macromolecules at the Blood-Brain Barrier Jane E. Preston, N. Joan Abbott and David J. Begley 6. Drug Delivery to the Ischemic Brain Brandon J. Thompson and Patrick T. Ronaldson 7. Delivery of Chemotherapeutics Across the Blood-Brain Barrier: Challenges and Advances Nancy D. Doolittle, Leslie L. Muldoon, Aliana Y. Culp and Edward A. Neuwelt 8. Delivery of Antihuman African Trypanosomiasis Drugs Across the Blood-Brain and Blood-CSF Barriers Gayathri N. Sekhar, Christopher P. Watson, Mehmet Fidanboylu, Lisa Sanderson and Sarah A. Thomas 9. Delivery of Therapeutic Peptides and Proteins to the CNS Therese S. Salameh and William A. Banks 10. Engineering and Pharmacology of Blood-Brain Barrier-Permeable Bispecific Antibodies Danica Stanimirovic, Kristin Kemmerich, Arsalan S. Haqqani and Graham K. Farrington 11. Pharmacological Significance of Prostaglandin E2 and D2 Transport at the Brain Barriers Masanori Tachikawa, Ken-ichi Hosoya and Tetsuya Terasaki 12. Steroids and the Blood-Brain Barrier: Therapeutic Implications Ken A. Witt and Karin E. Sandoval 13. Combination Approaches to Attenuate Hemorrhagic Transformation After tPA Thrombolytic Therapy in Patients with Poststroke Hyperglycemia/Diabetes Xiang Fan, Yinghua Jiang, Zhanyang Yu, Jing Yuan, Xiaochuan Sun, Shuanglin Xiang, Eng H. Lo and Xiaoying Wang 14. Aging, the Metabolic Syndrome, and Ischemic Stroke: Redefining the Approach for Studying the Blood-Brain Barrier in a Complex Neurological Disease Brandon P. Lucke-Wold, Aric F. Logsdon, Ryan C. Turner, Charles L. Rosen and Jason D. Huber 15. Drug Abuse and the Neurovascular Unit Richard D. Egleton and Thomas Abbruscato
1. ABC Transporter Regulation by Signaling at the Blood-Brain Barrier: Relevance to Pharmacology David S. Miller 2. P-glycoprotein Trafficking as a Therapeutic Target to Optimize CNS Drug Delivery Thomas P. Davis, Lucy Sanchez-Covarubias and Margaret E. Tome 3. Functional Expression of Drug Transporters in Glial Cells: Potential Role on Drug Delivery to the CNS Tamima Ashraf, Amy Kao and Reina Bendayan 4. Blood-Brain Barrier Na Transporters in Ischemic Stroke Martha E. O'Donnell 5. Transcytosis of Macromolecules at the Blood-Brain Barrier Jane E. Preston, N. Joan Abbott and David J. Begley 6. Drug Delivery to the Ischemic Brain Brandon J. Thompson and Patrick T. Ronaldson 7. Delivery of Chemotherapeutics Across the Blood-Brain Barrier: Challenges and Advances Nancy D. Doolittle, Leslie L. Muldoon, Aliana Y. Culp and Edward A. Neuwelt 8. Delivery of Antihuman African Trypanosomiasis Drugs Across the Blood-Brain and Blood-CSF Barriers Gayathri N. Sekhar, Christopher P. Watson, Mehmet Fidanboylu, Lisa Sanderson and Sarah A. Thomas 9. Delivery of Therapeutic Peptides and Proteins to the CNS Therese S. Salameh and William A. Banks 10. Engineering and Pharmacology of Blood-Brain Barrier-Permeable Bispecific Antibodies Danica Stanimirovic, Kristin Kemmerich, Arsalan S. Haqqani and Graham K. Farrington 11. Pharmacological Significance of Prostaglandin E2 and D2 Transport at the Brain Barriers Masanori Tachikawa, Ken-ichi Hosoya and Tetsuya Terasaki 12. Steroids and the Blood-Brain Barrier: Therapeutic Implications Ken A. Witt and Karin E. Sandoval 13. Combination Approaches to Attenuate Hemorrhagic Transformation After tPA Thrombolytic Therapy in Patients with Poststroke Hyperglycemia/Diabetes Xiang Fan, Yinghua Jiang, Zhanyang Yu, Jing Yuan, Xiaochuan Sun, Shuanglin Xiang, Eng H. Lo and Xiaoying Wang 14. Aging, the Metabolic Syndrome, and Ischemic Stroke: Redefining the Approach for Studying the Blood-Brain Barrier in a Complex Neurological Disease Brandon P. Lucke-Wold, Aric F. Logsdon, Ryan C. Turner, Charles L. Rosen and Jason D. Huber 15. Drug Abuse and the Neurovascular Unit Richard D. Egleton and Thomas Abbruscato
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"...it will be of immense value to those working in the area of CNS drug research or development and will also have a place in the libraries of academic institutions." --The Pharmaceutical Journal, November 2014
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