Phosphoinositides in Subcellular Targeting and Enzyme Activation

Herausgegeben von Stenmark, Harald

• Broschiertes Buch

Produktbeschreibung

Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.

Produktdetails

• Current Topics in Microbiology and Immunology .282
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-642-62299-1
• Softcover reprint of the original 1st edition 2004
• Seitenzahl: 228
• Erscheinungstermin: 16. Dezember 2012
• Englisch
• Abmessung: 235mm x 155mm x 13mm
• Gewicht: 353g
• ISBN-13: 9783642622991
• ISBN-10: 3642622992
• Artikelnr.: 39499597

Inhaltsangabe

List of Contents.- Phosphoinositide Involvement in Phagocytosis and Phagosome Maturation.- Regulation of Endocytosis by Phosphatidylinositol 4,5-Biphosphate and ENTH Proteins.- Membrane Targeting by Pleckstrin Homology Domains.- Protein Targeting to Endosomes and Phagosomes via FYVE and PX Domains.- Regulation of the Actin Cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in Neutrophil Function.- Nuclear Phosphoinositides and Their Functions.

Rezensionen

From the reviews:

"The book consists of seven chapters that focus on the various functions of PtdIns. ... summarises recent advances in the burgeoning field of inositol lipids and provides a snapshot of where the field stands in 2003. The field is moving rapidly but this volume will be a useful addition for many researchers who have only recently discovered that their favourite protein is regulated by PtdIns." (Shamshad Cockcroft, nature cell biology, Vol. 6 (6), June, 2004)