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Phosphonates, as we have shown in this book, phosphonate reagents and their diverse reactivity are very useful in the synthesis of biologically active products. Their use as substrates and key intermediates allows the synthesis of very complex structures to be carried out. The phosphonate-based methods compare favorably in terms of brevity (shortens) and use of simple reagents with the majority of the previously reported syntheses. Another advantage of the use of phosphonates is that the presence of phosphorus in starting materials and intermediates allows the course of each synthetic step to…mehr

Produktbeschreibung
Phosphonates, as we have shown in this book, phosphonate reagents and their diverse reactivity are very useful in the synthesis of biologically active products. Their use as substrates and key intermediates allows the synthesis of very complex structures to be carried out. The phosphonate-based methods compare favorably in terms of brevity (shortens) and use of simple reagents with the majority of the previously reported syntheses. Another advantage of the use of phosphonates is that the presence of phosphorus in starting materials and intermediates allows the course of each synthetic step to be followed by means of 31P-NMR spectroscopy. While this review presents a small sample of the uses of phosphonates in synthesis, they have been and will continue to be important reagents for synthetic chemists in the future.
Autorenporträt
La dott.ssa Abdou è professoressa di dottorato (2004, Regno Unito), ricercatrice principale del Centro Nazionale di Ricerca del Cairo. Grazie a diverse borse di studio, ha svolto il suo lavoro di ricerca negli Stati Uniti, in Germania, in Gran Bretagna e così via; ha pubblicato più di 170 articoli, Phosphorus Chem, e ha supervisionato più di 40 diplomi di laurea e dottorato. La dott.ssa Abdou è stata insignita di numerosi premi nazionali e internazionali.