Reconstructive Transplantation and Regenerative Surgery: The New Frontier, Volume Three in the Regenerative and Transplant Medicine series-explores this transformative discipline. This integration aims to overcome the limitations of traditional vascularized organ and tissue transplantation, offering innovative solutions through cutting-edge techniques. As regenerative surgery continues to evolve, this volume serves as a comprehensive resource, highlighting the latest advancements in graft immunomodulation, neuroregeneration, gene editing, diagnostic imaging, ischemia mitigation, and graft…mehr
Reconstructive Transplantation and Regenerative Surgery: The New Frontier, Volume Three in the Regenerative and Transplant Medicine series-explores this transformative discipline. This integration aims to overcome the limitations of traditional vascularized organ and tissue transplantation, offering innovative solutions through cutting-edge techniques. As regenerative surgery continues to evolve, this volume serves as a comprehensive resource, highlighting the latest advancements in graft immunomodulation, neuroregeneration, gene editing, diagnostic imaging, ischemia mitigation, and graft preservation. Authored by leading experts, this volume delves into crucial topics such as cell therapies, immunobiologics, neurobiologics, and targeted therapeutic strategies like local immunosuppressive implants and immunocloaking. It also covers cutting-edge diagnostic approaches, including non-invasive molecular imaging, nanotheranostics, and multimodal surveillance techniques. By addressing critical challenges in transplantation and regeneration, this book is an essential reference for surgeons, clinicians, trainees, scientists, and academics dedicated to advancing the field.
TABLE OF CONTENTS RECONSTRUCTIVE TRANSPLANTATION Part I - The Cutting Edge 1. The World’s Largest Single Center Experience in Face Transplantation Viola Stögner, Alexzandra Zdrava, and Bohdan Pomahac 2. Laryngotracheal Transplantation-Evolution and Experience Benjamin Laitman, and Eric Genden Part II - Unique Considerations and Emerging Indications 3. Lower Limb Transplantation - Pre-Clinical Insights and Patient Considerations Naga Anvesh Kodali, Omer Faruk Dirican, and Yalcin Kulahci 4. Penile Transplantation - Experience and Emerging Indications Janarthanan Ramu, Bedreddin Sazoglu, and Fatih Zor 5. Whole Eye Transplantation - Knowns and Unknowns Mariana Mayorquin, Gabriela Nava Márquez, Gustavo A. Rebolloso González REGENERATIVE SURGERY Part III - Targeted Technologies and Therapies 6. In-Situ, Implantable and Locally Injectable Drug Delivery - State of the Art Mishal Khan, Amogh Gorantla, and Praveen Kumar Vemula 7. Smart Sensors for Graft Health Monitoring Atul Sharma Vijay Gorantla, and Sameer Sonkusale 8. Opportunities in Covalent Tissue Modification for Graft-localized Drug Release Robert Kane, Johann Karunananthan, Michael Nicosa, Yalcin Kulahci, and Anna Valujskikh Part IV - Cellular and Regenerative Therapies 9. Cell Therapy and Immune Tolerance: State of the Art and Potential Applications in Reconstructive Transplantation Vinay Itte and David Leonard 10. Gene Editing Strategies for Immunomodulation Fatih Zor, Zeynep Demir, Vijay Gorantla, and Yalcin Kulahci Part V- Graft Preservation 11. Novel Oxygen Carrier Perfusates for Transplant Applications Vidya Surti, Amit Chandra Das, and Jelena Janjic 12. Preservation Technologies in Reconstructive Transplantation: Lessons from Solid Organ Experience Ellie Cohen, Josh Copus, and Varun Kopparthy Part VI - Tissue Engineering and Regenerative Biomaterials 13. Tracheal Tissue Engineering Çädä Duru and Siba Haykal 14. Thymus Tissue Engineering Gauri Kulkarni, Fatih Zor, Yalcin Kulahci, and Vijay Gorantla 15. Customized Bioresorbable Implants for Bone Fixation in Reconstructive Transplantation Matthew Criado, John Ohodnicki, Nikhita Joy, Mayur Gaikwad, Vijay Gorantla, and Prashant Kumta Part VII - Special Populations in Reconstructive Transplantation Hand and Face Transplantation in Teens and Young Adults - Unique Considerations Aarnav Gorantla and Mary Brooks Hall
TABLE OF CONTENTS RECONSTRUCTIVE TRANSPLANTATION Part I - The Cutting Edge 1. The World’s Largest Single Center Experience in Face Transplantation Viola Stögner, Alexzandra Zdrava, and Bohdan Pomahac 2. Laryngotracheal Transplantation-Evolution and Experience Benjamin Laitman, and Eric Genden Part II - Unique Considerations and Emerging Indications 3. Lower Limb Transplantation - Pre-Clinical Insights and Patient Considerations Naga Anvesh Kodali, Omer Faruk Dirican, and Yalcin Kulahci 4. Penile Transplantation - Experience and Emerging Indications Janarthanan Ramu, Bedreddin Sazoglu, and Fatih Zor 5. Whole Eye Transplantation - Knowns and Unknowns Mariana Mayorquin, Gabriela Nava Márquez, Gustavo A. Rebolloso González REGENERATIVE SURGERY Part III - Targeted Technologies and Therapies 6. In-Situ, Implantable and Locally Injectable Drug Delivery - State of the Art Mishal Khan, Amogh Gorantla, and Praveen Kumar Vemula 7. Smart Sensors for Graft Health Monitoring Atul Sharma Vijay Gorantla, and Sameer Sonkusale 8. Opportunities in Covalent Tissue Modification for Graft-localized Drug Release Robert Kane, Johann Karunananthan, Michael Nicosa, Yalcin Kulahci, and Anna Valujskikh Part IV - Cellular and Regenerative Therapies 9. Cell Therapy and Immune Tolerance: State of the Art and Potential Applications in Reconstructive Transplantation Vinay Itte and David Leonard 10. Gene Editing Strategies for Immunomodulation Fatih Zor, Zeynep Demir, Vijay Gorantla, and Yalcin Kulahci Part V- Graft Preservation 11. Novel Oxygen Carrier Perfusates for Transplant Applications Vidya Surti, Amit Chandra Das, and Jelena Janjic 12. Preservation Technologies in Reconstructive Transplantation: Lessons from Solid Organ Experience Ellie Cohen, Josh Copus, and Varun Kopparthy Part VI - Tissue Engineering and Regenerative Biomaterials 13. Tracheal Tissue Engineering Çädä Duru and Siba Haykal 14. Thymus Tissue Engineering Gauri Kulkarni, Fatih Zor, Yalcin Kulahci, and Vijay Gorantla 15. Customized Bioresorbable Implants for Bone Fixation in Reconstructive Transplantation Matthew Criado, John Ohodnicki, Nikhita Joy, Mayur Gaikwad, Vijay Gorantla, and Prashant Kumta Part VII - Special Populations in Reconstructive Transplantation Hand and Face Transplantation in Teens and Young Adults - Unique Considerations Aarnav Gorantla and Mary Brooks Hall
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