Rectal cancer; Dynamics of the tumor VEGF and the density of CD8+ TIL - Buka, David;Dvorak, Josef
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Examination of the effects of neoadjuvant chemoradiotherapy on VEGF expression and on the density of CD8+ tumor infiltrating lymphocytes (TIL) of rectal adenocarcinoma, by comparison of the VEGF expression and the density of CD8+ TIL in endoscopical biopsies before and resection specimens after the therapy, should have an clinical impact in the sense of prognosis of this disease. A trend of inferior prognosis was associated with decrease of VEGF expression. The limitation of our study is the number of patients (53), but it is not excluded that in a larger number of patients predictive or…mehr

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Produktbeschreibung
Examination of the effects of neoadjuvant chemoradiotherapy on VEGF expression and on the density of CD8+ tumor infiltrating lymphocytes (TIL) of rectal adenocarcinoma, by comparison of the VEGF expression and the density of CD8+ TIL in endoscopical biopsies before and resection specimens after the therapy, should have an clinical impact in the sense of prognosis of this disease. A trend of inferior prognosis was associated with decrease of VEGF expression. The limitation of our study is the number of patients (53), but it is not excluded that in a larger number of patients predictive or prognostic significance of the density of CD8+ TIL could be detected.
Autorenporträt
Mein Name ist David Buka, geboren 1982 in Trutnov in der Tschechischen Republik. Ich habe mein Studium der Allgemeinmedizin an der Karlsuniversität in Prag im Jahr 2009 abgeschlossen und arbeite derzeit als Radioonkologe im Lehrkrankenhaus in Hradec Kralove, Tschechische Republik.