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Rheumatoid arthritis (RA) is classified as a chronic disorder, meaning the progression of symptoms worsens over time. Patients may experience a rapid progression of the debilitating effects. As the synovium lining wears away or becomes inflamed, discomfort and risk for bone damage increase. Mesenchymal stem cells are known for their strong immunosuppressive by producing soluble mediators such as anti-inflammatory cytokines and might be useful as a therapeutic application in autoimmune diseases.