This book describes the status of clinical trials related to siRNA-based cancer therapy, as well as the remaining issues that need to be overcome to establish a successful therapy. It, then introduces various promising design strategies of delivery vehicles for stable and targeted siRNA delivery, including the prospects for future design.
This book describes the status of clinical trials related to siRNA-based cancer therapy, as well as the remaining issues that need to be overcome to establish a successful therapy. It, then introduces various promising design strategies of delivery vehicles for stable and targeted siRNA delivery, including the prospects for future design.
Prof. Loutfy H. Madkour is a professor of physical chemistry and nanoscience at Tanta University (Egypt). He received his BSc, MSc, and PhD in physical chemistry from the Cairo, Minia, and Tanta universities in Egypt, respectively. He has published 200 peer-reviewed original research articles, 20 review articles, and 8 books. He is an editorial board member of several international journals, including International Journal of Industrial Chemistry (IJIC-Springer), International Journal of Ground Sediment & Water, Global Drugs and Therapeutics, Chronicles of Pharmaceutical Science, Journal of Targeted Drug Delivery, UPI Journal of Pharmaceutical, Medical and Health Sciences, Global Journal of Nanomedicine, Clinical Pharmacology and Toxicology Research, Journal of Pharmacology & Pharmaceutical Research, LOJ Pharmacology & Clinical Research, CPQ Medicine, Pharmaceutical Sciences & Analytical Research Journal, Japan Journal of Research, Organic & Medicinal Chemistry International Journal, Nanotechnology & Applications, Materials Science Journal, Journal of Chemical Science and Chemical Engineering (Journals of- JCSCE), United Journal of Nanotechnology and Medicine, Clinical Practice (Therapy) journal, Journal of Materials New Horizons, Journal of Radiology and Medical Imaging. MedDocs Publishers, World Journal of Pharmacy and Pharmaceutical Sciences WJPPS and Journal of Material Science and Technology Research - RBM.
Inhaltsangabe
Chapter 01 Cancer epigenetic mechanisms-DNA methylomes, histone codes and miRNAs Chapter 02 Circulating miRNAs cancer biomarkers and epigenetic modifications in human cancer Chapter 03 The role of circulating microRNAs in diagnosis, prognosis and treatment targets of cancer and diseases Chapter 04 MicroRNAs potential in human cancer as therapeutic targets and novel biomarkers Chapter 05 Biological function of miRNAs and piRNAs targets in cancer tissues Chapter 06 Delivery strategies for siRNA and modifications process of RNAi therapeutics for cancer treatment Chapter 07 Clinical small interfering siRNA-based conjugate systems for RNAi cancer cells therapy Chapter 08 Potential targeted for siRNA in types of genetic diseases cancer therapeutics Chapter 09 Recent advanced of microRNA molecules delivery as anticancer drugs Chapter 10 DNA damaging cancer therapies and FDA novel drug approvals Chapter 11 Therapeutic potential role of miRNAs in pancreatic and prostate cancer cells Chapter 12 Regulation of microRNAs and their role in regeneration and cancer diseases Chapter 13 Novel classes of non-coding RNAs (ncRNAs) and cancer biology therapeutic targets Chapter 14 Advances in the inhibition and optimization of checkpoint kinases by small molecules for the treatment of cancer Chapter 15 Recent therapeutic prospects of microRNAs and siRNA delivery systems in cancer treatment nano-biotechnology
Chapter 01 Cancer epigenetic mechanisms-DNA methylomes, histone codes and miRNAs Chapter 02 Circulating miRNAs cancer biomarkers and epigenetic modifications in human cancer Chapter 03 The role of circulating microRNAs in diagnosis, prognosis and treatment targets of cancer and diseases Chapter 04 MicroRNAs potential in human cancer as therapeutic targets and novel biomarkers Chapter 05 Biological function of miRNAs and piRNAs targets in cancer tissues Chapter 06 Delivery strategies for siRNA and modifications process of RNAi therapeutics for cancer treatment Chapter 07 Clinical small interfering siRNA-based conjugate systems for RNAi cancer cells therapy Chapter 08 Potential targeted for siRNA in types of genetic diseases cancer therapeutics Chapter 09 Recent advanced of microRNA molecules delivery as anticancer drugs Chapter 10 DNA damaging cancer therapies and FDA novel drug approvals Chapter 11 Therapeutic potential role of miRNAs in pancreatic and prostate cancer cells Chapter 12 Regulation of microRNAs and their role in regeneration and cancer diseases Chapter 13 Novel classes of non-coding RNAs (ncRNAs) and cancer biology therapeutic targets Chapter 14 Advances in the inhibition and optimization of checkpoint kinases by small molecules for the treatment of cancer Chapter 15 Recent therapeutic prospects of microRNAs and siRNA delivery systems in cancer treatment nano-biotechnology
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