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This book tries to promote salivary glucose as a tool, fasting as well as random salivary glucose should evaluate. It establishes salivary glucose estimation as a diagnostic as well as a monitoring tool for diabetes mellitus. Higher concentration of salivary glucose was secreted in diabetes mellitus compared to control group. So salivary glucose appears as an indicator of serum glucose concentration in diabetic patients. Hence, fasting salivary glucose concentration can be used as a non-invasive diagnostic, as well as a monitoring tool to assess the glycemic status of diabetes mellitus patients.