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The 2nd all-Russia conference with international participation "Basic Research in Endocrinology: A Modern Strategy for the Development and Technologies of Personalized Medicine" was held in Novosibirsk on 24-25 November 2022. The purpose of this conference was to disseminate the latest basic and clinical findings in the fields of etiology, clinical characteristics, and modern diagnostics and treatments of endocrine disorders among various relevant specialists. The conference was intended for practicing endocrinologists, primary care physicians, medical geneticists, pediatric endocrinologists, pediatricians, and physician-scientists. The conference included plenary sessions, specialty sessions, satellite symposia, an open competition for young scientists, and the 2nd-in-Russia educational course for physicians: "Maturity Onset Diabetes of the Young (MODY): Molecular Genetic Determinants and a Personalized Approach to Patient Management."