Tuberculosis, caused by Mycobacterium tuberculosis is a major health concern worldwide. Protein kinases play a crucial part in regulation of various cellular processes including regulation of immune response to infections. Mycobacterium tuberculosis contains eleven genes coding for eukaryotic like Serine/Threonine Protein Kinases. These S/TPKs play very important roles in the biology of mycobacteria including infection process. In the current work, we have tried to understand the role of protein kinases in regulating mycobacterial infection of macrophages and to explore any relationship between macrophage Protein Kinase C and mycobacterial kinases.…mehr
Tuberculosis, caused by Mycobacterium tuberculosis is a major health concern worldwide. Protein kinases play a crucial part in regulation of various cellular processes including regulation of immune response to infections. Mycobacterium tuberculosis contains eleven genes coding for eukaryotic like Serine/Threonine Protein Kinases. These S/TPKs play very important roles in the biology of mycobacteria including infection process. In the current work, we have tried to understand the role of protein kinases in regulating mycobacterial infection of macrophages and to explore any relationship between macrophage Protein Kinase C and mycobacterial kinases.
Author is Assistant Professor in the department of Biotechnology, IGNT University, Amarkantak, MP, India. He did post doctoral research at Lund University, Sweden. Dr. Chaurasiya received PhD from Jawaharlal Nehru University, New Delhi, India and CSIR-Central Drug Research Institute, Lucknow, India. He has several papers in journals of high impact.
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