For more than 50 years, Sleisenger & Fordtran’s Gastrointestinal and Liver Disease has been the definitive reference for gastroenterology and hepatology physicians, students and trainees, and the broader multi-disciplinary GI care team. Now guided by a new generation of leaders in the field, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with all aspects of GI and liver disease-everything from basic science to new techniques and technologies. A consistent organization, more than 1,100 full-color illustrations, and…mehr
For more than 50 years, Sleisenger & Fordtran’s Gastrointestinal and Liver Disease has been the definitive reference for gastroenterology and hepatology physicians, students and trainees, and the broader multi-disciplinary GI care team. Now guided by a new generation of leaders in the field, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with all aspects of GI and liver disease-everything from basic science to new techniques and technologies. A consistent organization, more than 1,100 full-color illustrations, and clinically practicable algorithms ensure quick access to updated and current information on the diagnosis, treatment, and management of gastrointestinal and liver diseases. The 12th edition welcomes a new senior editorial team of Drs. Raymond T. Chung, David T. Rubin, and C. Mel Wilcox, and features many improvements and additions. * New and expanded discussions of eosinophilic disorders, MASLD (metabolic dysfunction-associated steatotic liver disease, formerly known as non-alcoholic fatty liver disease); the use of AI in endoscopy for improved detection of GI cancers; new treatments for viral hepatitis and autoimmune liver diseases; the expanded array of new treatments for inflammatory bowel disorders; and more * New chapters on Gastrointestinal and Hepatic Manifestations of Coronavirus Infection; Enterocolitis and Hepatitis Induced by Cancer Immunotherapy, and a new section on Neoplasia Involving Multiple Organs * Reliable coverage of a wide range of endoscopic procedures for diagnosis and treatment, including balloon dilatation, stent placement/removal, and the management of small bowel angioectasia * Quick-reference algorithms that summarize clinical decision making and practical approaches to patient management * A consistent, templated format throughout the text that enables quick retrieval of information, and more than 20 videos of endoscopic procedures * An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
Part I: Biology of the Gastrointestinal Tract 1. Cellular Growth and Neoplasia 2. Mucosal Immunology and Inflammation 3. The Enteric Microbiota 4. Gut Sensory Transduction 5. Biopsychosocial Issues in Gastroenterology Part II: Nutrition in Gastroenterology 6. Nutritional Principles and the Assessment of the Gastroenterology Patient 7. Nutritional Management 8. Obesity 9. Surgical and Endoscopic Treatment of Obesity 10. Feeding and Eating Disorders 11. Food Allergies Part III: Symptoms and Signs 12. Acute Abdominal Pain 13. Chronic Abdominal Pain 14. Symptoms of Esophageal Disease 15. Dyspepsia 16. Nausea and Vomiting 17. Diarrhea 18. Intestinal Gas 19. Fecal Incontinence 20. Constipation 21. Gastrointestinal Bleeding 22. Jaundice 23. Factitious Gastrointestinal Disease Part IV: Processes Involving Multiple Organs 24. Oral Diseases and Oral Manifestations of Gastrointestinal and Liver Diseases 25. Cutaneous Manifestations of Gastrointestinal and Liver Diseases 26. Diverticula of the Pharynx, Esophagus, Stomach, and Small Intestine 27. Abdominal Hernias and Gastric Volvulus 28. Foreign Bodies, Bezoars, and Caustic Ingestions 29. Abdominal Abscesses and Gastrointestinal Fistulas 30. Eosinophilic Disorders of the Gastrointestinal Tract 31. Protein-Losing Gastroenteropathy 32. Gastrointestinal and Hepatic Manifestations of Coronavirus Infection 33. Gastrointestinal Consequences of Infection with Human Immunodeficiency Virus 34. Gastrointestinal and Hepatic Complications of Solid Organ and Hematopoietic Cell Transplantation 35. Gastrointestinal and Hepatic Manifestations of Systemic Diseases 36. Vascular Lesions of the Gastrointestinal Tract 37. Surgical Peritonitis and Other Diseases of the Peritoneum, Mesentery, Omentum, and Diaphragm 38. Gastrointestinal and Hepatic Disorders in the Pregnant Patient 39. Acute and Chronic Gastrointestinal Side Effects of Radiation Therapy 40. Preparation for and Complications of GI Endoscopy Part V: Neoplasia Involving Multiple Organs 41. Gastrointestinal Lymphomas 42. Gastrointestinal Stromal Tumors 43. Neuroendocrine Tumors 44. Enterocolitis and Hepatitis Induced by Cancer Immunotherapy Part VI: Esophagus 45. Anatomy, Histology, Embryology, and Developmental Anomalies of the Esophagus 46. Esophageal Neuromuscular Function and Motility Disorders 47. Esophageal Disorders Caused by Medications, Trauma, and Infection 48. Gastroesophageal Reflux Disease 49. Barrett's Esophagus 50. Esophageal Tumors Part VII: Stomach and Duodenum 51. Anatomy, Histology and Developmental Anomalies of the Stomach and Duodenum 52. Gastric Neuromuscular Function and Neuromuscular Disorders 53. Gastric Secretion 54. Gastritis and Gastropathy 55. Peptic Ulcer Disease 56. Adenocarcinoma of the Stomach and Other Gastric Tumors Part VIII: Pancreas 57. Anatomy, Histology, Embryology, and Developmental Anomalies of the Pancreas 58. Pancreatic Secretion 59. Genetic Disorders of the Pancreas and Pancreatic Disorders in Childhood 60. Acute Pancreatitis 61. Chronic Pancreatitis 62. Pancreatic Cancer, Cystic Pancreatic Neoplasms, and Other Nonendocrine Pancreatic Tumors 63. Endoscopic Treatment of Pancreatic Disease Part IX: Biliary Tract 64. Anatomy, Histology, Embryology, Developmental Anomalies, and Pediatric Disorders of the Biliary Tract 65. Biliary Tract Motor Function and Dysfunction 66. Bile Formation and Bile Acid Cycling in Health and Disease 67. Gallstone Disease 68. Treatment of Gallstone Disease 69. Acalculous Biliary Pain, Acute Acalculous Cholecystitis, Cholesterolosis, Adenomyomatosis, and Gallbladder Polyps 70. Primary and Secondary Sclerosing Cholangitis 71. Tumors of the Bile Ducts, Gallbladder, and Ampulla 72. Endoscopic and Radiologic Treatment of Biliary Disease Part X: Liver 73. Embryology, Anatomy, Histology, and Developmental Anomalies of the Liver 74. Liver Physiology and Energy Metabolism 75. Liver Chemistry and Function Tests 76. Overview of Cirrhosis 77. Hemochromatosis 78. Wilson Disease 79. Other Inherited Metabolic Disorders of the Liver 80. Hepatitis A 81. Hepatitis B 82. Hepatitis C 83. Hepatitis D 84. Hepatitis E 85. Hepatitis Caused by Other Viruses 86. Bacterial, Parasitic, and Fungal Infections of the Liver, including Liver Abscess 87. Vascular Diseases of the Liver 88. Alcoholic-Associated Liver Disease 89. Metabolic dysfunction-associated steatotic liver disease/Nonalcoholic fatty liver disease 90. Liver Disease Caused by Drugs 91. Liver Disease Caused by Anesthetics, Chemicals, Toxins, and Herbal and Dietary Supplements 92. Autoimmune Hepatitis 93. Primary Biliary Cholangitis 94. Portal Hypertension and Variceal Bleeding 95. Ascites and Spontaneous Bacterial Peritonitis 96. Hepatic Encephalopathy, Hepatorenal Syndrome, Hepatopulmonary Syndrome, and Other Systemic Complications of Liver Disease 97. Acute Liver Failure 98. Hepatic Tumors and Cysts 99. Liver Transplantation Part XI: Small and Large Intestine 100. Anatomy, Histology, Embryology, and Developmental Anomalies of the Small and Large Intestine 101. Small Intestinal Motor and Sensory Function and Dysfunction 102. Colonic Motor and Sensory Function and Dysfunction 103. Intestinal Electrolyte Absorption and Secretion 104. Digestion and Absorption of Carbohydrate, Protein, and Fat 105. Digestion and Absorption of Micronutrients 106. Maldigestion and Malabsorption 107. Small Intestinal Bacterial Overgrowth 108. Short Bowel Syndrome 109. Celiac Disease 110. Tropical Diarrhea and Malabsorption 111. Whipple Disease 112. Infectious Enteritis and Proctocolitis 113. Food Poisoning 114. Antibiotic-Associated Diarrhea and Clostridium difficile Infection 115. Intestinal Protozoa 116. Intestinal Worms 117. Epidemiology, Pathogenesis and Diagnosis of Inflammatory Bowel Diseases 118. Management of Inflammatory Bowel Diseases 119. Ileostomies, Colostomies, and Anastomoses 120. Intestinal Ischemia 121. Intestinal Ulcerations 122. Appendicitis 123. Diverticular Disease of the Colon 124. Irritable Bowel Syndrome 125. Intestinal Obstruction 126. Ileus and Pseudo-Obstruction Syndromes 127. Tumors of the Small Intestine 128. Colonic Polyps and Polyposis Syndromes 129. Colorectal Cancer 130. Other Diseases of the Colon 131. Anal Diseases Part XII: Additional Treatments for Patients with Gastrointestinal and Liver Disease 132. Complementary, Alternative, and Integrative Medicine 133. Palliative Care Medicine in Patients with Advanced Gastrointestinal and Hepatic Disease
Part I: Biology of the Gastrointestinal Tract 1. Cellular Growth and Neoplasia 2. Mucosal Immunology and Inflammation 3. The Enteric Microbiota 4. Gut Sensory Transduction 5. Biopsychosocial Issues in Gastroenterology Part II: Nutrition in Gastroenterology 6. Nutritional Principles and the Assessment of the Gastroenterology Patient 7. Nutritional Management 8. Obesity 9. Surgical and Endoscopic Treatment of Obesity 10. Feeding and Eating Disorders 11. Food Allergies Part III: Symptoms and Signs 12. Acute Abdominal Pain 13. Chronic Abdominal Pain 14. Symptoms of Esophageal Disease 15. Dyspepsia 16. Nausea and Vomiting 17. Diarrhea 18. Intestinal Gas 19. Fecal Incontinence 20. Constipation 21. Gastrointestinal Bleeding 22. Jaundice 23. Factitious Gastrointestinal Disease Part IV: Processes Involving Multiple Organs 24. Oral Diseases and Oral Manifestations of Gastrointestinal and Liver Diseases 25. Cutaneous Manifestations of Gastrointestinal and Liver Diseases 26. Diverticula of the Pharynx, Esophagus, Stomach, and Small Intestine 27. Abdominal Hernias and Gastric Volvulus 28. Foreign Bodies, Bezoars, and Caustic Ingestions 29. Abdominal Abscesses and Gastrointestinal Fistulas 30. Eosinophilic Disorders of the Gastrointestinal Tract 31. Protein-Losing Gastroenteropathy 32. Gastrointestinal and Hepatic Manifestations of Coronavirus Infection 33. Gastrointestinal Consequences of Infection with Human Immunodeficiency Virus 34. Gastrointestinal and Hepatic Complications of Solid Organ and Hematopoietic Cell Transplantation 35. Gastrointestinal and Hepatic Manifestations of Systemic Diseases 36. Vascular Lesions of the Gastrointestinal Tract 37. Surgical Peritonitis and Other Diseases of the Peritoneum, Mesentery, Omentum, and Diaphragm 38. Gastrointestinal and Hepatic Disorders in the Pregnant Patient 39. Acute and Chronic Gastrointestinal Side Effects of Radiation Therapy 40. Preparation for and Complications of GI Endoscopy Part V: Neoplasia Involving Multiple Organs 41. Gastrointestinal Lymphomas 42. Gastrointestinal Stromal Tumors 43. Neuroendocrine Tumors 44. Enterocolitis and Hepatitis Induced by Cancer Immunotherapy Part VI: Esophagus 45. Anatomy, Histology, Embryology, and Developmental Anomalies of the Esophagus 46. Esophageal Neuromuscular Function and Motility Disorders 47. Esophageal Disorders Caused by Medications, Trauma, and Infection 48. Gastroesophageal Reflux Disease 49. Barrett's Esophagus 50. Esophageal Tumors Part VII: Stomach and Duodenum 51. Anatomy, Histology and Developmental Anomalies of the Stomach and Duodenum 52. Gastric Neuromuscular Function and Neuromuscular Disorders 53. Gastric Secretion 54. Gastritis and Gastropathy 55. Peptic Ulcer Disease 56. Adenocarcinoma of the Stomach and Other Gastric Tumors Part VIII: Pancreas 57. Anatomy, Histology, Embryology, and Developmental Anomalies of the Pancreas 58. Pancreatic Secretion 59. Genetic Disorders of the Pancreas and Pancreatic Disorders in Childhood 60. Acute Pancreatitis 61. Chronic Pancreatitis 62. Pancreatic Cancer, Cystic Pancreatic Neoplasms, and Other Nonendocrine Pancreatic Tumors 63. Endoscopic Treatment of Pancreatic Disease Part IX: Biliary Tract 64. Anatomy, Histology, Embryology, Developmental Anomalies, and Pediatric Disorders of the Biliary Tract 65. Biliary Tract Motor Function and Dysfunction 66. Bile Formation and Bile Acid Cycling in Health and Disease 67. Gallstone Disease 68. Treatment of Gallstone Disease 69. Acalculous Biliary Pain, Acute Acalculous Cholecystitis, Cholesterolosis, Adenomyomatosis, and Gallbladder Polyps 70. Primary and Secondary Sclerosing Cholangitis 71. Tumors of the Bile Ducts, Gallbladder, and Ampulla 72. Endoscopic and Radiologic Treatment of Biliary Disease Part X: Liver 73. Embryology, Anatomy, Histology, and Developmental Anomalies of the Liver 74. Liver Physiology and Energy Metabolism 75. Liver Chemistry and Function Tests 76. Overview of Cirrhosis 77. Hemochromatosis 78. Wilson Disease 79. Other Inherited Metabolic Disorders of the Liver 80. Hepatitis A 81. Hepatitis B 82. Hepatitis C 83. Hepatitis D 84. Hepatitis E 85. Hepatitis Caused by Other Viruses 86. Bacterial, Parasitic, and Fungal Infections of the Liver, including Liver Abscess 87. Vascular Diseases of the Liver 88. Alcoholic-Associated Liver Disease 89. Metabolic dysfunction-associated steatotic liver disease/Nonalcoholic fatty liver disease 90. Liver Disease Caused by Drugs 91. Liver Disease Caused by Anesthetics, Chemicals, Toxins, and Herbal and Dietary Supplements 92. Autoimmune Hepatitis 93. Primary Biliary Cholangitis 94. Portal Hypertension and Variceal Bleeding 95. Ascites and Spontaneous Bacterial Peritonitis 96. Hepatic Encephalopathy, Hepatorenal Syndrome, Hepatopulmonary Syndrome, and Other Systemic Complications of Liver Disease 97. Acute Liver Failure 98. Hepatic Tumors and Cysts 99. Liver Transplantation Part XI: Small and Large Intestine 100. Anatomy, Histology, Embryology, and Developmental Anomalies of the Small and Large Intestine 101. Small Intestinal Motor and Sensory Function and Dysfunction 102. Colonic Motor and Sensory Function and Dysfunction 103. Intestinal Electrolyte Absorption and Secretion 104. Digestion and Absorption of Carbohydrate, Protein, and Fat 105. Digestion and Absorption of Micronutrients 106. Maldigestion and Malabsorption 107. Small Intestinal Bacterial Overgrowth 108. Short Bowel Syndrome 109. Celiac Disease 110. Tropical Diarrhea and Malabsorption 111. Whipple Disease 112. Infectious Enteritis and Proctocolitis 113. Food Poisoning 114. Antibiotic-Associated Diarrhea and Clostridium difficile Infection 115. Intestinal Protozoa 116. Intestinal Worms 117. Epidemiology, Pathogenesis and Diagnosis of Inflammatory Bowel Diseases 118. Management of Inflammatory Bowel Diseases 119. Ileostomies, Colostomies, and Anastomoses 120. Intestinal Ischemia 121. Intestinal Ulcerations 122. Appendicitis 123. Diverticular Disease of the Colon 124. Irritable Bowel Syndrome 125. Intestinal Obstruction 126. Ileus and Pseudo-Obstruction Syndromes 127. Tumors of the Small Intestine 128. Colonic Polyps and Polyposis Syndromes 129. Colorectal Cancer 130. Other Diseases of the Colon 131. Anal Diseases Part XII: Additional Treatments for Patients with Gastrointestinal and Liver Disease 132. Complementary, Alternative, and Integrative Medicine 133. Palliative Care Medicine in Patients with Advanced Gastrointestinal and Hepatic Disease
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