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Strategic information systems (SIS) incorporate the realisation of the strategic importance of Information Systems for Organisational competitiveness, as well as the methods, tools and the processes to achieve it. The alignment of Information Technology (IT) and business strategies lie at the core of any effort to use IT for gaining and sustaining competitive advantage. Business and IT strategies alignment is not a one-off process, but a continuous endeavour which requires the setup of an appropriate Strategic Information System Planning mechanism. The link between technological innovation and growth is not a coincidence. The speed of technological progress and change has become aggressive in recent years so that organisations need to respond quickly to new environmental changes and challenges. Organisations need to continuously renew their technological capacity in information technology, to ensure their prosperity and sustainability.