Strategies to Mitigate the Toxicity of Cancer Therapeutics, Volume 155 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters, each of which is written by an international board of authors.
Strategies to Mitigate the Toxicity of Cancer Therapeutics, Volume 155 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters, each of which is written by an international board of authors.
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Autorenporträt
Dr. Gewirtz received his PhD degree from Mt. Sinai School of Medicine of the City University of New York. He has been at Virginia Commonwealth University in the Department of Pharmacology and Toxicology and as a member of the Massey Cancer Center for his entire career. His work has been in the areas of cancer chemotherapy and radiotherapy, originally in breast cancer, but more recently extending to lung cancer, prostate cancer and head and neck cancer. His interests have long been in the nature of alternative tumor responses to therapy, most prominently autophagy and senescence. He has long argued that senescence is not an irreversible form of growth arrest, that senescence could represent one form of tumor dormancy and furthermore that recovery from senescence could contribute to disease recurrence. His most recent publication describes the impact of the senolytic agent, ABT-263 (navitoclax) on breast and lung tumor cells induced into senescence by cancer chemotherapy and radiati
on.
Inhaltsangabe
Contributors in this volume include: Annemieke Kavelaars Nitesh Kumar Imad Damaj Ningjun Li Maryam Lustberg Hamid Akbarali Fadi Salloum
