Systems Biology of Cancer
Herausgeber: Thiagalingam, Sam
Systems Biology of Cancer
Herausgeber: Thiagalingam, Sam
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An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
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An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Produktdetails
- Produktdetails
- Verlag: Cambridge University Press
- Seitenzahl: 548
- Erscheinungstermin: 9. April 2015
- Englisch
- Abmessung: 246mm x 185mm x 30mm
- Gewicht: 1406g
- ISBN-13: 9780521493390
- ISBN-10: 0521493390
- Artikelnr.: 41610436
- Herstellerkennzeichnung
- Libri GmbH
- Europaallee 1
- 36244 Bad Hersfeld
- gpsr@libri.de
- Verlag: Cambridge University Press
- Seitenzahl: 548
- Erscheinungstermin: 9. April 2015
- Englisch
- Abmessung: 246mm x 185mm x 30mm
- Gewicht: 1406g
- ISBN-13: 9780521493390
- ISBN-10: 0521493390
- Artikelnr.: 41610436
- Herstellerkennzeichnung
- Libri GmbH
- Europaallee 1
- 36244 Bad Hersfeld
- gpsr@libri.de
Contributors; Preface; Part I. Introduction to Modular Organization of the
Networks of Gene Functions and Cancer: 1. Systems biology of cancer
progression Sam Thiagalingam; 2. Lessons from cancer genome sequencing
Antoine Ho and Jeremy S. Edwards; 3. Application of bioinformatics to
analyze the expression of tissue-specific and housekeeping genes in cancer
Xijin Ge; Part II. Alterations in the Regulatory Networks of Fundamental
Cellular and Molecular Events in Cancer: 4. Events at DNA replication
origins and genome stability Kathleen R. Nevis, Kimberly L. Raiford, Cyrus
Vaziri and Jeanette Gowen Cook; 5. Systems biology approaches bring new
insights in the understanding of global gene regulatory mechanisms and
their deregulation in cancer Arnaud Krebs and László Tora; 6. Regulation
and dysregulation of protein synthesis in cancer cells Michael J. Clemens,
Androulla Elia and Simon J. Morley; Part III. Networks of Events
Responsible for the Manifestation of Aberrant Genetic and Epigenetic Codes
in Cancer: 7. Genomic instability and carcinogenesis Mark E. Burkard and
Prasad V. Jallepalli; 8. Epigenomic code José Ignacio Martín-Subero and
Manel Esteller; 9. MicroRNA epigenetic systems and cancer Holly Lewis and
Aurora Esquela-Kerscher; 10. Dietary and environmental influences on the
genomic and epigenomic codes in cancer Hamid Abdolmaleky and Jin-Rong Zhou;
Part IV. Functional Networks of Events that Modulate Phenotypic
Manifestation of Cancer: 11. Regulatory signaling networks in cell
transformation and cancer Yashaswi Shrestha and William C. Hahn; 12. RAS
signaling networks Douglas Faller; 13. The PI3K pathway in cancer Amancio
Carnero; 14. TGFß and BMP signaling in cancer Panagiotis Papageorgis,
Arthur W. Lambert, Sait Ozturk and Sam Thiagalingam; 15. The Wnt signaling
network in cancer Johanna Apfel, Jignesh R. Parikh, Patricia Reischmann,
Rob M. Ewing, Oliver Müller, Yu Xia and Isabel Dominguez; 16. Apoptotic
pathways and cancer Jian Yu and Lin Zhang; 17. Molecular links between
inflammation and cancer Paola Allavena, Giovanni Germano and Alberto
Mantovani; 18. Cancer metastasis Sait Ozturk, Arthur W. Lambert, Chen Khuan
Wong, Panagiotis Papageorgis and Sam Thiagalingam; 19. Cancer metabolism
Dimitrios Anastasiou, Jason W. Locasale and Matthew G. Vander Heiden; 20.
Tumor microenvironment: blood vascular system in cancer metastasis
Shantibhusan Senapati, Rakesh K. Singh and Surinder K. Batra; Part V.
Current State of the Evolving MMMN Cancer Progression Models of Cancer: 21.
Genetic alterations in glioblastoma multiforme Giselle Y. López, Marc
Samsky, Rosanne Jones, Cory Adamson and Hai Yan; 22. Breast cancer Arthur
W. Lambert, Sait Ozturk, Chen Khuan Wong, Panagiotis Papageorgis and Sam
Thiagalingam; 23. The role of growth factor induced changes in cell fate in
prostate cancer progression Min Yu, Gromoslaw A. Smolen, Daniel A. Haber
and Shyamala Maheswaran; 24. Colon cancer Anthony Scott and Zhenghe Wang;
25. Biology of human stomach cancer Bryan G. Sauer and Steven M. Powell;
26. Pancreatic cancer Sergii Ivakhno, Kristopher Frese, Simon Tavare,
Christine Iacobuzio-Donahue and David Tuveson; 27. Deregulated signaling
networks in lung cancer Anurag Singh; 28. Modular signaling in
hematopoietic malignancies Adam Lerner; Part VI. Applications of
Comprehensive Cancer Progression Models in the Fight against Cancer: 29.
Role of network biology and network medicine in early detection of cancer
Asad Umar and Simon Rosenfeld; 30. Systems biology in cancer biomarkers for
early detection, diagnosis and prognosis Sudhir Srivastava and Karl
Krueger; 31. Prognosis of cancer Sharyn Katz and Wafik S. El-Deiry; 32.
Cancer pharmacogenomics: challenges, promises, and its application to
cancer drug discovery Lihua Yu and Kevin Webster; Index.
Networks of Gene Functions and Cancer: 1. Systems biology of cancer
progression Sam Thiagalingam; 2. Lessons from cancer genome sequencing
Antoine Ho and Jeremy S. Edwards; 3. Application of bioinformatics to
analyze the expression of tissue-specific and housekeeping genes in cancer
Xijin Ge; Part II. Alterations in the Regulatory Networks of Fundamental
Cellular and Molecular Events in Cancer: 4. Events at DNA replication
origins and genome stability Kathleen R. Nevis, Kimberly L. Raiford, Cyrus
Vaziri and Jeanette Gowen Cook; 5. Systems biology approaches bring new
insights in the understanding of global gene regulatory mechanisms and
their deregulation in cancer Arnaud Krebs and László Tora; 6. Regulation
and dysregulation of protein synthesis in cancer cells Michael J. Clemens,
Androulla Elia and Simon J. Morley; Part III. Networks of Events
Responsible for the Manifestation of Aberrant Genetic and Epigenetic Codes
in Cancer: 7. Genomic instability and carcinogenesis Mark E. Burkard and
Prasad V. Jallepalli; 8. Epigenomic code José Ignacio Martín-Subero and
Manel Esteller; 9. MicroRNA epigenetic systems and cancer Holly Lewis and
Aurora Esquela-Kerscher; 10. Dietary and environmental influences on the
genomic and epigenomic codes in cancer Hamid Abdolmaleky and Jin-Rong Zhou;
Part IV. Functional Networks of Events that Modulate Phenotypic
Manifestation of Cancer: 11. Regulatory signaling networks in cell
transformation and cancer Yashaswi Shrestha and William C. Hahn; 12. RAS
signaling networks Douglas Faller; 13. The PI3K pathway in cancer Amancio
Carnero; 14. TGFß and BMP signaling in cancer Panagiotis Papageorgis,
Arthur W. Lambert, Sait Ozturk and Sam Thiagalingam; 15. The Wnt signaling
network in cancer Johanna Apfel, Jignesh R. Parikh, Patricia Reischmann,
Rob M. Ewing, Oliver Müller, Yu Xia and Isabel Dominguez; 16. Apoptotic
pathways and cancer Jian Yu and Lin Zhang; 17. Molecular links between
inflammation and cancer Paola Allavena, Giovanni Germano and Alberto
Mantovani; 18. Cancer metastasis Sait Ozturk, Arthur W. Lambert, Chen Khuan
Wong, Panagiotis Papageorgis and Sam Thiagalingam; 19. Cancer metabolism
Dimitrios Anastasiou, Jason W. Locasale and Matthew G. Vander Heiden; 20.
Tumor microenvironment: blood vascular system in cancer metastasis
Shantibhusan Senapati, Rakesh K. Singh and Surinder K. Batra; Part V.
Current State of the Evolving MMMN Cancer Progression Models of Cancer: 21.
Genetic alterations in glioblastoma multiforme Giselle Y. López, Marc
Samsky, Rosanne Jones, Cory Adamson and Hai Yan; 22. Breast cancer Arthur
W. Lambert, Sait Ozturk, Chen Khuan Wong, Panagiotis Papageorgis and Sam
Thiagalingam; 23. The role of growth factor induced changes in cell fate in
prostate cancer progression Min Yu, Gromoslaw A. Smolen, Daniel A. Haber
and Shyamala Maheswaran; 24. Colon cancer Anthony Scott and Zhenghe Wang;
25. Biology of human stomach cancer Bryan G. Sauer and Steven M. Powell;
26. Pancreatic cancer Sergii Ivakhno, Kristopher Frese, Simon Tavare,
Christine Iacobuzio-Donahue and David Tuveson; 27. Deregulated signaling
networks in lung cancer Anurag Singh; 28. Modular signaling in
hematopoietic malignancies Adam Lerner; Part VI. Applications of
Comprehensive Cancer Progression Models in the Fight against Cancer: 29.
Role of network biology and network medicine in early detection of cancer
Asad Umar and Simon Rosenfeld; 30. Systems biology in cancer biomarkers for
early detection, diagnosis and prognosis Sudhir Srivastava and Karl
Krueger; 31. Prognosis of cancer Sharyn Katz and Wafik S. El-Deiry; 32.
Cancer pharmacogenomics: challenges, promises, and its application to
cancer drug discovery Lihua Yu and Kevin Webster; Index.
Contributors; Preface; Part I. Introduction to Modular Organization of the
Networks of Gene Functions and Cancer: 1. Systems biology of cancer
progression Sam Thiagalingam; 2. Lessons from cancer genome sequencing
Antoine Ho and Jeremy S. Edwards; 3. Application of bioinformatics to
analyze the expression of tissue-specific and housekeeping genes in cancer
Xijin Ge; Part II. Alterations in the Regulatory Networks of Fundamental
Cellular and Molecular Events in Cancer: 4. Events at DNA replication
origins and genome stability Kathleen R. Nevis, Kimberly L. Raiford, Cyrus
Vaziri and Jeanette Gowen Cook; 5. Systems biology approaches bring new
insights in the understanding of global gene regulatory mechanisms and
their deregulation in cancer Arnaud Krebs and László Tora; 6. Regulation
and dysregulation of protein synthesis in cancer cells Michael J. Clemens,
Androulla Elia and Simon J. Morley; Part III. Networks of Events
Responsible for the Manifestation of Aberrant Genetic and Epigenetic Codes
in Cancer: 7. Genomic instability and carcinogenesis Mark E. Burkard and
Prasad V. Jallepalli; 8. Epigenomic code José Ignacio Martín-Subero and
Manel Esteller; 9. MicroRNA epigenetic systems and cancer Holly Lewis and
Aurora Esquela-Kerscher; 10. Dietary and environmental influences on the
genomic and epigenomic codes in cancer Hamid Abdolmaleky and Jin-Rong Zhou;
Part IV. Functional Networks of Events that Modulate Phenotypic
Manifestation of Cancer: 11. Regulatory signaling networks in cell
transformation and cancer Yashaswi Shrestha and William C. Hahn; 12. RAS
signaling networks Douglas Faller; 13. The PI3K pathway in cancer Amancio
Carnero; 14. TGFß and BMP signaling in cancer Panagiotis Papageorgis,
Arthur W. Lambert, Sait Ozturk and Sam Thiagalingam; 15. The Wnt signaling
network in cancer Johanna Apfel, Jignesh R. Parikh, Patricia Reischmann,
Rob M. Ewing, Oliver Müller, Yu Xia and Isabel Dominguez; 16. Apoptotic
pathways and cancer Jian Yu and Lin Zhang; 17. Molecular links between
inflammation and cancer Paola Allavena, Giovanni Germano and Alberto
Mantovani; 18. Cancer metastasis Sait Ozturk, Arthur W. Lambert, Chen Khuan
Wong, Panagiotis Papageorgis and Sam Thiagalingam; 19. Cancer metabolism
Dimitrios Anastasiou, Jason W. Locasale and Matthew G. Vander Heiden; 20.
Tumor microenvironment: blood vascular system in cancer metastasis
Shantibhusan Senapati, Rakesh K. Singh and Surinder K. Batra; Part V.
Current State of the Evolving MMMN Cancer Progression Models of Cancer: 21.
Genetic alterations in glioblastoma multiforme Giselle Y. López, Marc
Samsky, Rosanne Jones, Cory Adamson and Hai Yan; 22. Breast cancer Arthur
W. Lambert, Sait Ozturk, Chen Khuan Wong, Panagiotis Papageorgis and Sam
Thiagalingam; 23. The role of growth factor induced changes in cell fate in
prostate cancer progression Min Yu, Gromoslaw A. Smolen, Daniel A. Haber
and Shyamala Maheswaran; 24. Colon cancer Anthony Scott and Zhenghe Wang;
25. Biology of human stomach cancer Bryan G. Sauer and Steven M. Powell;
26. Pancreatic cancer Sergii Ivakhno, Kristopher Frese, Simon Tavare,
Christine Iacobuzio-Donahue and David Tuveson; 27. Deregulated signaling
networks in lung cancer Anurag Singh; 28. Modular signaling in
hematopoietic malignancies Adam Lerner; Part VI. Applications of
Comprehensive Cancer Progression Models in the Fight against Cancer: 29.
Role of network biology and network medicine in early detection of cancer
Asad Umar and Simon Rosenfeld; 30. Systems biology in cancer biomarkers for
early detection, diagnosis and prognosis Sudhir Srivastava and Karl
Krueger; 31. Prognosis of cancer Sharyn Katz and Wafik S. El-Deiry; 32.
Cancer pharmacogenomics: challenges, promises, and its application to
cancer drug discovery Lihua Yu and Kevin Webster; Index.
Networks of Gene Functions and Cancer: 1. Systems biology of cancer
progression Sam Thiagalingam; 2. Lessons from cancer genome sequencing
Antoine Ho and Jeremy S. Edwards; 3. Application of bioinformatics to
analyze the expression of tissue-specific and housekeeping genes in cancer
Xijin Ge; Part II. Alterations in the Regulatory Networks of Fundamental
Cellular and Molecular Events in Cancer: 4. Events at DNA replication
origins and genome stability Kathleen R. Nevis, Kimberly L. Raiford, Cyrus
Vaziri and Jeanette Gowen Cook; 5. Systems biology approaches bring new
insights in the understanding of global gene regulatory mechanisms and
their deregulation in cancer Arnaud Krebs and László Tora; 6. Regulation
and dysregulation of protein synthesis in cancer cells Michael J. Clemens,
Androulla Elia and Simon J. Morley; Part III. Networks of Events
Responsible for the Manifestation of Aberrant Genetic and Epigenetic Codes
in Cancer: 7. Genomic instability and carcinogenesis Mark E. Burkard and
Prasad V. Jallepalli; 8. Epigenomic code José Ignacio Martín-Subero and
Manel Esteller; 9. MicroRNA epigenetic systems and cancer Holly Lewis and
Aurora Esquela-Kerscher; 10. Dietary and environmental influences on the
genomic and epigenomic codes in cancer Hamid Abdolmaleky and Jin-Rong Zhou;
Part IV. Functional Networks of Events that Modulate Phenotypic
Manifestation of Cancer: 11. Regulatory signaling networks in cell
transformation and cancer Yashaswi Shrestha and William C. Hahn; 12. RAS
signaling networks Douglas Faller; 13. The PI3K pathway in cancer Amancio
Carnero; 14. TGFß and BMP signaling in cancer Panagiotis Papageorgis,
Arthur W. Lambert, Sait Ozturk and Sam Thiagalingam; 15. The Wnt signaling
network in cancer Johanna Apfel, Jignesh R. Parikh, Patricia Reischmann,
Rob M. Ewing, Oliver Müller, Yu Xia and Isabel Dominguez; 16. Apoptotic
pathways and cancer Jian Yu and Lin Zhang; 17. Molecular links between
inflammation and cancer Paola Allavena, Giovanni Germano and Alberto
Mantovani; 18. Cancer metastasis Sait Ozturk, Arthur W. Lambert, Chen Khuan
Wong, Panagiotis Papageorgis and Sam Thiagalingam; 19. Cancer metabolism
Dimitrios Anastasiou, Jason W. Locasale and Matthew G. Vander Heiden; 20.
Tumor microenvironment: blood vascular system in cancer metastasis
Shantibhusan Senapati, Rakesh K. Singh and Surinder K. Batra; Part V.
Current State of the Evolving MMMN Cancer Progression Models of Cancer: 21.
Genetic alterations in glioblastoma multiforme Giselle Y. López, Marc
Samsky, Rosanne Jones, Cory Adamson and Hai Yan; 22. Breast cancer Arthur
W. Lambert, Sait Ozturk, Chen Khuan Wong, Panagiotis Papageorgis and Sam
Thiagalingam; 23. The role of growth factor induced changes in cell fate in
prostate cancer progression Min Yu, Gromoslaw A. Smolen, Daniel A. Haber
and Shyamala Maheswaran; 24. Colon cancer Anthony Scott and Zhenghe Wang;
25. Biology of human stomach cancer Bryan G. Sauer and Steven M. Powell;
26. Pancreatic cancer Sergii Ivakhno, Kristopher Frese, Simon Tavare,
Christine Iacobuzio-Donahue and David Tuveson; 27. Deregulated signaling
networks in lung cancer Anurag Singh; 28. Modular signaling in
hematopoietic malignancies Adam Lerner; Part VI. Applications of
Comprehensive Cancer Progression Models in the Fight against Cancer: 29.
Role of network biology and network medicine in early detection of cancer
Asad Umar and Simon Rosenfeld; 30. Systems biology in cancer biomarkers for
early detection, diagnosis and prognosis Sudhir Srivastava and Karl
Krueger; 31. Prognosis of cancer Sharyn Katz and Wafik S. El-Deiry; 32.
Cancer pharmacogenomics: challenges, promises, and its application to
cancer drug discovery Lihua Yu and Kevin Webster; Index.