Faheem Shahzad Khan

T Regulatory cells in type 2 diabetes mellitus

Herausgegeben:Afzal, Nadeem

• Broschiertes Buch

Produktbeschreibung

Various complications arise during the course of type 2 diabetes mellitus (T2DM) including the production of autoantibodies. These autoantibodies could be the consequence of some dysregulation in immune regulatory system. Since T regulatory cells (Tregs) are the key player in the maintenance of immune regulation, this study was designed to enumerate the percentage of Tregs in T2DM patients. This was a comparative study, which included 84 subjects. Subjects without diabetes were labelled as Group-I (28 healthy individuals), Group-II included 28 T2DM patients who had diabetes of 1-5 years duration, and Group-III had 28 T2DM patients with more than 5 years of diabetes. Tregs were enumerated by FACScalibur flow Cytometer (BD) using BD CellQuest Pro software. Data were analysed using SPSS 20.0. Highest mean ± SD of percentage of nTregs was observed in group-I (5.6±2.8), followed by group-III (1.7±1.5) and group-II (1.4±1.7). When three groups were compared, a statistically significantdifference was observed among the groups (p value 0.000). Group-II was significantly different group-III (p=0.000) but there was no significant difference between group-II and group-III.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 80
• Erscheinungstermin: 2. September 2016
• Englisch
• Abmessung: 220mm x 150mm x 5mm
• Gewicht: 137g
• ISBN-13: 9783659941313
• ISBN-10: 365994131X
• Artikelnr.: 45982357

Autorenporträt

Trabalho como gestor sénior de laboratório e doutorando no departamento de Imunologia da Universidade de Ciências da Saúde de Lahore, no Paquistão. Tenho 11 publicações em revistas bem indexadas. Também trabalho como formador principal de biossegurança no Paquistão e fui selecionado como bolseiro de segurança sanitária futura (2015) pela Health Security Partners (EUA).