The Handbook of Dopamine

Volume 32
Herausgeber: Cragg, Stephanie J; Walton, Mark

• Gebundenes Buch

Produktbeschreibung

The Handbook of Dopamine captures current understanding of dopamine biology in the brain, including anatomical organization of dopamine neurons, their molecular and genetic diversity, synaptic and circuit connectivity, receptor function and signalling, through to diverse roles in behaviors and finally, dysfunction in disease. This volume compiles a comprehensive set of perspectives from a large number of leading scientists working in dopamine research. The volume describes the current state-of-the-field, summarizing knowledge that has been transformed in the last decade through the advent and application of sophisticated new technologies.

Produktdetails

• Verlag: Elsevier Science
• Seitenzahl: 576
• Erscheinungstermin: 28. August 2025
• Englisch
• Abmessung: 282mm x 218mm x 36mm
• Gewicht: 1737g
• ISBN-13: 9780443298677
• ISBN-10: 044329867X
• Artikelnr.: 70898773

Inhaltsangabe

Section 1: Development, diversity, and connectivity
1. The dopamine system from an evolutionary perspective
Sten Grillner and Brita Robertson
2. Molecular heterogeneity of midbrain dopamine neurons
Rajeshwar Awatramani and Jean-Francois Poulin
3. Building an action circuit with nigrostriatal dopaminergic neurons and
striatonigral neurons
Huaibin Cai and Charles Gerfen
4. Anatomy of dopamine neuron projections: Axonal arbors, varicosities, and
synapses
Louis-Eric Trudeau and Raphaelle Denis
5. Dopamine neuron connectomes: Inputs and outputs
Mitsuko Watabe-Uchida and Ryunosuke Amo
Section 2: Dopamine neuron physiology and dopamine release regulation
6. Electrical patterns of activity in dopamine midbrain neurons in vivo
Jochen Roeper, Birgit Liss, Zayd Khaliq, and Carmen C. Canavier
7. Computational modeling of midbrain dopamine neurons
Carmen C. Canavier, Christopher Knowlton, Birgit Liss, Zayd Khaliq, and
Jochen Roeper
8. Axonal dopamine release: Molecular mechanisms
Pascal S. Kaeser
9. Somatodendritic dopamine release
Margaret E. Rice, Takuya Hikima, Paul Witkovsky, and Jyoti C. Patel
10. Axonal regulation of dopamine transmission by striatal neuromodulators
Stephanie J. Cragg, David Sulzer, and Kathryn Todd
11. Dopamine transporters and the nanoscale organization of the dopamine
axon
Aske Lykke Ejdrup, Matthew Lycas, Freja Herborg, and Ulrik Gether
12. Beyond dopamine: Cotransmission by dopamine neurons
Riccardo Melani and Nicolas X. Tritsch
Section 3: Dopamine signalling: Receptors, postsynaptic integration and
plasticity
13. Unveiling activation mechanisms and intrinsic divergence of dopamine
receptors based on experimentally determined structures
Sung Joon Won, Kuo Hao Lee, and Lei Shi
14. Dopamine receptor drugs and their applications
J. Robert Lane and Alessandro Bonifazi
15. Postsynaptic integration and plasticity in the striatum
Sho Yagishita
16. Dopamine signaling roles in the extrastriatal basal ganglia
Jerome Baufreton
17. Postsynaptic integration and plasticity in the prefrontal cortex
Paul G. Anastasiades, Guillermo Gonzalez-Burgos, and Wen-Jun Gao
Section 4: Dopamine mechanisms of learning and reinforcement
18. The dopamine reward prediction error signal
Wolfram Schultz
19. Diversity of encoding: Reward to aversion
Naoshige Uchida, Mitsuko Watabe-Uchida, and Isobel Green
20. Dopamine beyond temporal-difference reinforcement learning
Kaue Machado Costa and Geoffrey Schoenbaum
21. Habits and dopamine
Jay Bertran-Gonzalez and Bernard W. Balleine
22. Dopamine for performance evaluation-Insights from songbirds
Vikram Gadagkar
23. Striking parallels between the dopaminergic systems of flies and
mammals
Kristijan D. Jovanoski and Scott Waddell
24. Reinforcement learning with dopamine: A convergence of natural and
artificial intelligence
Paul Masset and Samuel J. Gershman
Section 5: Dopamine function in motivated behavior
25. Dopamine and the temporal control of behavior
Joseph Paton
26. Volition and vigor
Joshua T. Dudman and Luke T. Coddington
27. Why the new definition of "anhedonia" misses the mark on dopamine
function: Studies of effort-based aspects of motivation and selection of
voluntary physical activity
John D. Salamone and Merce Correa
28. Exploration and behavioral variability
Philippe Faure
29. Role of dopamine in adaptively tuning motivational bias to the current
environment
Roshan Cools, Hanneke E.M. Den Ouden, and Egbert Hartstra
30. Sex differences in dopamine systems involved in motivation and reward
Christopher A. Turner, Noah Bass, Ivette L. Gonzalez, and Jill B. Becker
31. Dopamine and appetite
Camila Saenz and Stephanie L. Borgland
Section 6: Dopamine dysregulation: From neurology to psychiatry
32. Neuronal design and determinants of selective neuronal vulnerability of
dopaminergic neurons in Parkinson’s disease
Enrico Zampese, James Moran, and D. James Surmeier
33. Understanding human dopamine neuron biology in Parkinson’s patient
cells
Gizem Onal, Maria Claudia Caiazza, Parnaz Sharifi, Iona Thomas-Wright,
Johanna L. Hoffmann, Rachel Heon-Roberts, and Richard Wade-Martins
34. Dopamine replacement for Parkinson’s disease: Clinical approaches and
experimental
underpinnings
M. Angela Cenci, Kristina Rosqvist, and Per Odin
35. Dopamine modulation of synaptic transmission in drug addiction
Maria Reva and Christian L EURUscher
36. Molecular reprogramming of D1 and D2 dopaminoceptive medium spiny
neurons in substance use disorder
Caleb J. Browne and Eric J. Nestler
37. Human dopamine systems in addiction disorders
Nora D. Volkow and Peter Manza
38. Apathy and impulsivity in neurological and psychiatric disorders
Youssuf Saleh and Masud Husain
39. Dopamine dysfunction in psychosis
Robert A. Mccutcheon and Chambrez-Zita Zauchenberger
40. Dopamine systems in impulsive-compulsive behavior
Trevor W. Robbins and Jeffrey W. Dalley