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Beloved for decades, TheImmune System continues to be the perfect introduction to immunology for undergraduate and medical school students. The Sixth Edition is more readable and approachable than ever before-edited for clarity by three experienced classroom instructors with modern students in mind. Updated to include more clinical and health connections, along with exciting research and clear, schematic art, The Immune System blends a human-oriented lens on the immune system with pedagogical efficacy to encourage contextual understanding over memorization. Now with Smartwork online homework, the Sixth Edition offers more options for flexible and focused assessment. Noteworthy in the Sixth Edition: * New research and health applications demonstrate the connections of immunology to medicine, including the LEAP study on peanut allergies, COVID-19, and new immunotherapies. * Chapter 12 has been split into two shorter, more focused chapters on unconventional T cells and natural killer cells to improve clarity on these complicated topics. Similarly, Chapters 2 and 3 on innate immunity have been reorganized for student-friendliness. * Smartwork online homework replaces InQuizitive, offering more instructor control over assignments and assessment. * Updated End-of-Chapter Questions provide more opportunities for critical thinking and data interpretation. * Updated clinical photos of signs and rashes on a range of skin tones prepare students for medical careers.