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This book elaborates about Epiphyllum oxypetalum, commonly referred to as Queen of the Night, is a captivating decorative plant admired for its aromatic flowers that bloom at night and its historical applications in traditional medicine, especially by the Shoshone tribe for heart-related issues. It has been used historically to address various health concerns, including bleeding disorders, respiratory problems, and circulatory conditions. The plant is rich in bioactive compounds like glycosides, saponins, tannins, and terpenoids, which are responsible for its documented antioxidant, anti-inflammatory, antibacterial, and antimicrobial effects. Although it offers these advantages, it remains insufficiently studied in contemporary science, highlighting a significant opportunity for further research in medicinal and pharmacological fields.