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Periodontal disease is a leading community health matter and the evolution of successful remedy to nurse the disease and restore periodontal tissue is prime aim of present medical science. Regeneration of periodontal tissue is possibly one of the most complicated action to happen in the body. Langer and colleagues put forward tissue engineering as a potential method for regenerating the missing periodontal tissues. Tissue engineering is an integrative field, which associate the implementation of the concept and techniques of engineering and life sciences to assist in the evolution of biological substitute to reconstruct, support or boost the role of injured tissues and organs. The aim of practicing tissue engineering as restorative function has been to tackle its capacity to make use of selected and primed cells at the same time with suitable blend of regulatory factors, to permit production and specialization of cells and matrix.