Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The uncinate fasciculus is a white matter tract in the human brain that connects parts of the limbic system such as the hippocampus and amygdala in the temporal lobe with frontal ones such as the orbitofrontal cortex. Its function is unknown though it is affected in several psychiatric conditions. It is the last white matter tract to mature in the human brain. The uncinate fasciculus is a hook-shaped bundle that links the forward portions of the temporal lobe with the inferior frontal gyrus and the lower surfaces of the frontal lobe. It does this by arising lateral to the amygdala and hippocampus in the temporal lobe curving in an upward pathway behind the external capsule inward of the insular cortex and continuing up into the posterior part of the orbital gyrus.
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