UV AND HPLC Method Development and Method Validation of Nevirapine - Choudhury, Tirthankar
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This research work focused on UV and RP-HPLC method and method validation of Nevirapine accurately and economically. UV spectrophotometric method and mehod development for Nevirapine obeyed Beer's law as depicted by linearity of the developed method. A reverse phase HPLC (RP-HPLC) method is described for the determination of nevirapine in tablet dosage forms. Chromatography was carried on an ODS column using a mixture of methanol and water (89:11 v/v) as the mobile phase at a flow rate of 1 mL/min with detection at 284 nm. The method was validated by determining its sensitivity, accuracy and…mehr

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Produktbeschreibung
This research work focused on UV and RP-HPLC method and method validation of Nevirapine accurately and economically. UV spectrophotometric method and mehod development for Nevirapine obeyed Beer's law as depicted by linearity of the developed method. A reverse phase HPLC (RP-HPLC) method is described for the determination of nevirapine in tablet dosage forms. Chromatography was carried on an ODS column using a mixture of methanol and water (89:11 v/v) as the mobile phase at a flow rate of 1 mL/min with detection at 284 nm. The method was validated by determining its sensitivity, accuracy and precision. The proposed method is simple, economical, fast, accurate and precise, hence can be applied for routine quality control of nevirapine in bulk and tablet dosage forms.
Autorenporträt
Tirthankar Choudhury, M. Pharm (Química Farmacêutica), PhD, F.I.C., C.C: - o autor completou o B. Pharm no ano de 2005, completou o M. Pharm em 2008 e completou o PhD em 2012. O autor também completou o F.I.C. (2021) e o C.C. (2022) do Govt. da Índia. O autor tem mais de 25 publicações em revistas internacionais e 2 patentes concedidas.