Rolf Hubmayr / Claude Lenfant (eds.)

Ventilator-Induced Lung Injury

Herausgeber: Dreyfuss, Didier; Hubmayr, Rolf; Saumon, Georges

• Gebundenes Buch

Produktbeschreibung

This reference surveys current best practices in the prevention and management of ventilator-induced lung injury (VILI) and spans the many pathways and mechanisms of VILI including cell injury and repair, the modulation of alveolar-capillary barrier properties, and lung and systemic inflammatory consequences of injurous mechanical ventilation. Considering many emerging therapeutic options, this guide also reviews the wide array of clinical studies on lung protection strategies and approaches to ARDS patients at risk for VILI.

Produktdetails

• Verlag: CRC Press
• Seitenzahl: 766
• Erscheinungstermin: 21. März 2006
• Englisch
• Abmessung: 235mm x 157mm x 45mm
• Gewicht: 1240g
• ISBN-13: 9780849337161
• ISBN-10: 084933716X
• Artikelnr.: 21590503

Autorenporträt

Didier Dreyfuss, Georges Saumon, Rolf Hubmayr

Inhaltsangabe

INTRODUCTION. Ventilator-Induced Lung Injury: From Bench to Bedside and
Back Again. ACUTE MANIFESTATIONS OF VILI. Pathological Features of ARDS and
VILI. Imaging Alveolar Mechanics During VILI. Response of Cellular Plasma
Membrane to Mechanical Stress. Passive and Active Changes in Microcascular
Permeability During Lung Distension. Meodynamic Interactions During VILI.
Gene Expression During VILI. Lung Mechanics and VILI. Effects of Acute Lung
Distension on the Cytokine Network. SUBACUTE VILI. Inflammation Cascade
During VILI. Apoptosis in the Lung and Remote Organs During VILI. Systemic
Consequences of VILI/Evidence for Organ Failure Causation. Interaction of
VILI with Previous Lung Alterations. Modulation of Lung Injury by
Hypercapnia. Potential Implications of Genomics in the Prevention and
Treatment of VILI. CLINICAL IMPLICATIONS OF VILI. Lung Imaging of
Ventilator-Associated Injury. The Future of Lung Imaging of VILI/VALI.
Modulation of the Cytokine Network by Lung Protective Mechanical
Ventilation Strategies. Role of Tidal Volume and of Peep in the Reduction
of Ventilator-Associated Lung Injury. A Critical Review of Randomized
Controls of Tidal Volume Reduction During ARDS. PREVENTION AND TREATMENT OF
VILI. The Importance of Protocol-Directed Management for Research on Lung
Protective Ventilation. How to Design Clinical Studies for the Prevention
of Ventilator-Associated Lung Injury? Potential Benefits and Risks of
Partial Liquid Ventilation During Acute Lung Injury. Prospects for
Reduction of VILI with Surfactant. Rationale for HFO Ventilations in Acute
Lung Injury