Viral Therapy of Human Cancers

Herausgeber: Sinkovics, Joseph G.; Horvath, Joseph

• Broschiertes Buch

Produktbeschreibung

Featuring contributions from leading authorities, this pioneering work explores the potential for viruses to act as oncolytic and anti-tumor agents for the treatment of cancers. It details the cancer-combative properties exhibited by viruses in nature, genetically engineered viruses, and viral oncolysates as evidenced in basic and experimental studies and includes coverage of measles, influenza, and herpes simplex viruses; parvoviruses; poliovirus recombinants; Newcastle disease viruses and viral oncolysates; and vaccinia viral lysates. Comparing the viral therapy of cancer with alternative biological therapeutic approaches, the book lists more than fifty oncolytic adenovirus preparations.

Produktdetails

• Verlag: CRC Press
• Seitenzahl: 850
• Erscheinungstermin: 13. Dezember 2019
• Englisch
• Abmessung: 229mm x 152mm x 45mm
• Gewicht: 1205g
• ISBN-13: 9780367393342
• ISBN-10: 0367393344
• Artikelnr.: 58440758

Autorenporträt

Joseph G. Sinkovics , Joseph C. Horvath

Inhaltsangabe

Introduction o Progressive Development of the Viral Therapy of Human
Cancers: A Personal Narrative Account Joseph G. Sinkovics o New Biological
Therapeutics: Competitors or Collaborators in Viral Therapy for Human
Cancers Joseph G. Sinkovics o Naturally Oncolytic Viruses o Measles Virus:
Improving Natural Oncolytic Properties by Genetic Engineering Christoph
Springfield, Adele Fielding, Kah-Whye Peng, Eva Galanis, Stephen J.
Russell, and Roberto Cattaneo o Newcastle Disease Virus: Anti-tumor Immune
Memory and Its Activation for Control of Residual Tumor Cells and
Improvement of Patient Survival Volker Schirrmacher o Newcastle Disease
Virus: Its Oncolytic Properties Joseph C. Horvath o Influenza A Viruses
with Deletions in the NS1 Gene: A Rational Approach to Develop Oncolytic
Viruses Michael Bergmann and Thomas Muster o Vesicular Stomatitis Virus: An
Oncolytic Agent Rebecca A. C. Taylor, Jennifer M. Paterson, and John C.
Bell o Parvoviruses as Anti-Cancer Agents Jean Rommelaere, Nathalia Giese,
Celina Cziepluch, and Jan J. Cornelis o Viral Oncolysates o Newcastle
Disease Virus Oncolysate in the Management of Stage III (AJCC) Malignant
Melanoma William A. Cassel, Douglas R. Murray, and Zbigniew L. Olkowski o
Vaccinia Viral Lysates in Immunotherapy of Melanoma Peter Hersey o
Genetically Engineered Oncolytic Viruses o Fusogenic Oncolytic Herpes
Simplex Viruses for Therapy of Solid Tumors Xinping Fu, Mikihito Nakamori,
and Xiaoliu Zhang o Poliovirus Recombinants Against Malignant Glioma
Melinda Merrill, David Solecki, and Matthias Gromeier o Oncolytic Viruses
that Depend on Loss of RB or p53 Frank McCormick