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One of the discoveries found in virus-host interactions is the so-called viral RNA silencing suppressor proteins which play a key role in viral infection process. As a practical point of view, these proteins can also be in vitro manipulated and in vivo employed by the researchers for specific aims such as enhancing exogenous protein expression in plant and increasing viral infection in low-efficiency inoculation systems. This book reviews the applications of these particular proteins with the aforementioned goals and discuss their potential use in coming research projects. Reading this book would help graduate students, researchers and professors in all bio-molecular disciplines to get inspired for conducting novel experiments leading to knowledge-based improvement in laboratory technologies.