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Adolescents affected by osteosarcoma and amputated can tell us stories of struggle, overcoming, patience and courage in search of a cure. Adolescents who are victims of amputation weave links with the intra-family network and with friends, school and the health team, with spirituality, sport and leisure as a coping strategy. Analysing this weaving contributes to fostering relationships of affection and trust between the adolescent, their family and their social network. This coping strategy has the potential to promote health by strengthening autonomy and contributing to individualised nursing care. This book is aimed at health professionals who deal with adolescent cancer patients, with a view to reflecting on early diagnosis and the importance of stimulating their bonds.