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This book explores Alzheimer's disease through the prism of bioinorganic chemistry, examining its history, global impact and current challenges. It details the biology of amyloid plaques and tau neurofibrils, as well as the role of metals such as copper in neurodegenerative processes. The focus is on copper, discussing its involvement in amyloid plaques, its disrupted homeostasis and its effects on neurons. The book offers an analysis of metal deposits in the brain using X-ray absorption spectroscopy (XAS). In conclusion, it summarizes current knowledge, the implications for research and treatment, and suggests avenues for future research. Although I am an expert in XAS, my involvement is limited as I am not involved in research using synchrotron radiation or particle gas pedals, which restricts my role in these new directions.