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The Zika virus reshaped global health by exposing gaps in surveillance, clinical care, and vector control. Zika Virus provides a comprehensive account of the pathogen, from molecular biology and transmission ecology to diagnostics, clinical management, and public health response. It traces ZIKV's shift from sylvatic cycles to urban epidemics, underscores its links with congenital Zika syndrome and neurological disease, and distils lessons for preparedness in a warming, urbanizing world. The book covers virion structure, genetics, evolution, host-pathogen interactions, epidemiology, outbreak investigation, and clinical features across age groups, with emphasis on pregnancy and pediatrics. A major focus is Aedes biology and Integrated Vector Management, spanning environmental, chemical, biological, and genetic strategies and resistance monitoring. Emerging innovations-biosensors, genomic surveillance, machine learning, and eco-friendly nanotechnology are presented with guidance forthe One Health application. Designed for researchers, clinicians, practitioners, and students, the book translates complex science into actionable strategies for Zika prevention and control.