Kenneth Kee

A Simple Guide to Congenital Adrenal Hyperplasia, Diagnosis, Treatment and Related Conditions (eBook, ePUB)

• Format: ePub

Produktbeschreibung

This book describes Congenital Adrenal Hyperplasia, Diagnosis and Treatment and Related Diseases

Congenital adrenal hyperplasia (CAH) is a cluster of hereditary disorders that have an effect on the adrenal glands.

The adrenal glands sit on top of the kidneys and secrete the hormones cortisol and aldosterone.

CAH is produced by genetic defects that stop these glands from producing these 2 hormones either completely or at normal rates.

Everybody has 2 of these glands, one on top of each kidney.

CAH is produced by 3 deficiencies:

1. Too little cortisol

The adrenal glands of infants born with CAH cannot produce enough of the hormone cortisol.

Cortisol is occasionally called the stress hormone since it is secreted when the patient is under stress.

It helps to regulate blood sugar.

This hormone has an effect on:
a. Energy levels,
b. Blood sugar levels,
c. Blood pressure, and
d. The body's response to stress, illness, and injury.

2. Too little aldosterone

In about 75% of cases, infants born with CAH cannot produce enough of the hormone aldosterone, which assists the body to maintain the proper level of sodium (salt) and water and helps regulate blood pressure.

Aldosterone assists the kidneys to function and balance the electrolytes.

3. Too much androgen

In certain cases, infants born with CAH secrete too much of male hormones, androgens.

Appropriate levels of these hormones are required for normal growth and development in both boys and girls.

CAH can also produce imbalances in the hormone adrenaline, which influences:
a. Blood sugar levels,
b. Blood pressure, and
c. The body's response to stress.

The hormone imbalance most often observed in CAH cases is too little of a substance called 21-hydroxylase.

The adrenal glands require 21-hydroxylase to produce proper quantities of hormones.

This type of CAH is occasionally termed as 21-hydroxylase deficiency.

A small number of cases of CAH are produced by deficiency in a substance similar to 21-hydroxylase, termed 11-hydroxylase.

This type of CAH is occasionally termed as 11-hydroxylase deficiency.

In CAH due to 11-hydroxylase deficiency, the adrenal glands produce too little cortisol and too many androgens.

This type of CAH does not cause aldosterone deficiency.

Other very rare types of CAH are:
4. 3-betahydroxy-steroid dehydrogenase deficiency,
5. Lipoid CAH, and
6. 17-hydroxylase deficiency.

The defect that produces CAH is inherited from both parents and passed to their child.

Classical CAH is responsible for around 95 % of all CAH cases.

It mostly happens in infants and young children.

The adrenal glands normally produce cortisol and aldosterone with the help of an enzyme termed 21-hydroxylase.

With classical CAH this enzyme is absent, which indicates the adrenal glands cannot produce these hormones.

Also, the body starts producing too much of a male sex hormone called testosterone.

This induces masculine features to happen in girls and develop early in boys.

Non-classical or late-onset CAH is a milder form that happens in older children and young adults.

CAH is an autosomal recessive disorder.

TABLE OF CONTENT
Introduction
Chapter 1 Congenital Adrenal Hyperplasia
Chapter 2 Causes
Chapter 3 Symptoms
Chapter 4 Diagnosis
Chapter 5 Treatment
Chapter 6 Prognosis
Chapter 7 Adrenal Insufficiency (Updated)
Chapter 8 Life and Death of an Adrenal Gland
Epilogue

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Produktdetails

• Verlag: Kenneth Kee
• Erscheinungstermin: 26. Mai 2021
• Englisch
• ISBN-13: 9781005047696
• Artikelnr.: 75904952

Autorenporträt

Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.
He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.
Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.
Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.
He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.
He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.
Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.
Beyond his medical career, Dr. Kee is also an author.
He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.
Over time, he published various books, many of which provide simple and accessible guides to different health conditions.
His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.
His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.
Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.

Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:
"A Family Doctor's Tale"
This book is a blend of Dr. Kee's personal experiences and his reflections on being a family doctor in Singapore. It's a great choice if you're looking for a narrative that combines both medical knowledge and human stories.
"Specialized Medical Conditions"
Books like **"Congestive Heart Failure: Diagnosis and Treatment"** focus on specific conditions, offering in-dept...