Kenneth Kee

A Simple Guide to Fibro-sarcoma, Diagnosis, Treatment and Related Conditions (eBook, ePUB)

• Format: ePub

Produktbeschreibung

This book describes Fibro-sarcoma, Diagnosis and Treatment and Related Diseases

Sarcoma is the cancer that starts in the soft tissues of the body.

The soft tissues are the connective tissues that maintain everything in place, such as:
1. Nerves, tendons, and ligaments
2. Fibrous and deep skin tissues
3. Blood and lymph vessels
4. Fat and muscle

Soft tissue sarcomas consist of more than 50 types.

Fibro-sarcoma comprises about 5 percent of primary bone sarcomas.

It is infrequent, involving about 1 in 2 million people.

Fibro-sarcoma is so named since it is made of malignant spindled fibroblasts or myofibroblasts.

It has its beginning in the fibrous tissue that encloses tendons, ligaments, and muscles.

While it can originate in any area of the body, it is most frequent in the legs or trunk.

Fibro-sarcomas are considered a malignant neoplasm composed of fibroblasts that may have differing quantities of collagen production and having 'herringbone' architecture.

Fibro-sarcomas can be sub-classified into 2 types:
1. Infantile or congenital fibro-sarcomas, or
2. Adult-type fibro-sarcomas.

Infantile fibro-sarcomas seldom metastasize while adult-type fibro-sarcomas are very malignant.

In infants under the age of 1, it is termed infantile fibro-sarcoma (IFS) and is normally slow-growing.

Infantile Fibro-sarcoma is a malignant tumor of infancy normally seen in children below age 1.

The most frequent site of the tumor is the arms and legs followed next by the trunk.

In older children and adults, it is termed adult form fibro-sarcoma.

Adult Fibro-sarcoma often involves the deep soft tissues of the extremities, trunk, head, and neck.

The exact cause of fibro-sarcoma is not known but genetics may play a role.

Certain factors may raise the danger of developing the disease, such as some inherited disorders:
Familial adenomatous polyposis
Li-Fraumeni syndrome
Neurofibromatosis type 1

Other risk factors may be:
Previous radiation therapy
Certain chemicals, such as thorium dioxide, vinyl chloride, or arsenic
Lymph edema, a swelling in the arms and legs

The symptoms of fibro-sarcoma can be faint at first.

The patient might notice a painless lump or swelling under the skin.

As it develops, it can disrupt the ability to use the limb.

If it begins in the abdomen, the patient probably will not notice until it is of significant size.

Fibro-sarcoma tumors normally vary from 3-8 cm in size.

Molecular analysis of the tumor is done to detect the fusion of ETV6 and NTRK3 genes; such detection of this particular mutation can help confirm a diagnosis of Infantile Fibro-sarcoma.

A diagnosis of Fibro-sarcoma is normally established by excluding the possibility of other tumors.

It is a diagnosis made through exclusion and may involve the imaging tests.

Contrast-enhanced MRI is the favored method to evaluate tumors of the extremities or pelvis and will provide data of a tumor's size, margins, signal density, degree of necrosis and vascularization.

If a mass is detected, the only way to confirm fibro-sarcoma is with a biopsy.

Surgical excision is the main treatment for localized fibro-sarcomas.

Intramuscular tumors should have a compartmental total excision.

If there is extra-compartmental growth, or if the tumor has not reach the insertion of the muscle, a wide-surgical resection would be proper, with the aim of obtaining tumor-free margins.

The prognosis of fibro-sarcomas is poor.

The 5-year survival rates for high-grade fibro-sarcomas are about 30%

TABLE OF CONTENT
Introduction
Chapter 1 Fibro-sarcoma
Chapter 2 Causes
Chapter 3 Symptoms
Chapter 4 Diagnosis
Chapter 5 Treatme...

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Produktdetails

• Verlag: Kenneth Kee
• Erscheinungstermin: 6. Februar 2022
• Englisch
• ISBN-13: 9781005158347
• Artikelnr.: 75904546

Autorenporträt

Dr. Kenneth Kee is a well-known medical doctor from Singapore who has been practicing medicine since 1972.
He graduated from the University of Singapore and furthered his studies with a Master of Science in Health Management in 1991, followed by a Ph.D. in Healthcare Administration in 1993.
Dr. Kee established Kee Clinic in 1974, located in the Holland Drive area of Singapore. The clinic has been a prominent feature of the community, offering general medical services for 5 decades.
Dr Kee also served his country Singapore as a national service police Inspector at night from 1975 to 1985 while working at his clinic during the day.
He had served as a police guard to the Woodland Petroleum Tanks at night during the Indonesian Confrontation period, took part in police rounds at night in the Beach Road area and taught First aid and emergency resuscitation to Police recruits.
He received the Singapore Police Bicentennial 2020 Medallion on 1st March 2024 as recognition for his work in the Singapore Police.
Even as he grew older, Dr. Kee continued to work actively in his clinic, although he eventually reduced his consultation hours.
Beyond his medical career, Dr. Kee is also an author.
He started writing about medical conditions in 2007, using blogs and other online platforms to share his knowledge with a broader audience.
Over time, he published various books, many of which provide simple and accessible guides to different health conditions.
His works include "A Family Doctor's Tale," "My Personal Singapore History," and numerous medical guides, available through platforms like Amazon.
His books often combine his personal experiences as a family doctor with insights into Singapore's healthcare system and history.
Dr. Kee has written extensively on health topics, contributing to both medical literature and general knowledge resources.

Dr. Kenneth Kee has written numerous books, primarily focused on health education and personal experiences as a family doctor. Some of his notable titles include:
"A Family Doctor's Tale"
This book is a blend of Dr. Kee's personal experiences and his reflections on being a family doctor in Singapore. It's a great choice if you're looking for a narrative that combines both medical knowledge and human stories.
"Specialized Medical Conditions"
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