Acute Promyelocytic Leukemia (eBook, PDF)

A Clinical Guide
Redaktion: Abla, Oussama; Sanz, Miguel A.; Lo Coco, Francesco

• Format: PDF

Produktbeschreibung

First comprehensive text on acute promyelocytic leukemia in the last ten years

Summarizes historical, current, and future treatment strategies

Highlights the most recent therapeutic recommendations for relapsed disease

Written by top experts in the field

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Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Springer International Publishing
• Seitenzahl: 274
• Erscheinungstermin: 25. April 2018
• Englisch
• ISBN-13: 9783319642574
• Artikelnr.: 52996016

Autorenporträt

Oussama Abla, MD The Hospital for Sick Children and University of Toronto Division of Hematology/Oncology Toronto, ON Canada   Francesco Lo-Coco, MD Professor of Hematology University of Tor Vergata Rome Italy   Miguel A. Sanz, MD Centro de Investigacio¿n Biome¿dica en Red de Cäncer Madrid Spain

Inhaltsangabe

History of APL.- Molecular Targets of Treatment in APL.- The Leukemic Stem Cell.- The Molecular Genetics of APL.- APL Coagulopathy.- Early Death in APL.- Prognostic Factors in APL.- First-line therapy for APL: Chemotherapy-based approach.- First-line Therapy: ATRA-ATO/Reduced Chemotherapy Approach.- Cure of APL without Chemotherapy.- Minimal Residual Disease in APL.- Treatment of refractory and relapsed APL.- Hematopoietic Stem Cell Transplantation in APL.- APL in Children.- Management of APL in the Elderly.- Special Situations in APL.- APL in Developing Countries: A Chemotherapy-Based Approach.- APL in Developing Countries: ATO based Approach.- Therapy-Related APL.- Rare Acute Leukemia Variants involving Retinoic Acid Receptor Genes.- Management of Treatment-Related Complications in APL.

Rezensionen

"This is a clinical guide to acute promyelocytic leukemia or APL, and it is the first book dedicated entirely to APL. Starting with an engaging historical account, the book provides a comprehensive overview of the clinical and basic aspects of APL, once regarded as the most fatal type of acute myeloid leukemia, but now considered the most curable. ... general practitioners and trainees also will find this book worth exploring ... ." (Ravi Salgia, Doody's Book Reviews, January 04, 2019)